Importance The benefits of vitamin D, omega-3 fatty acids, and exercise in disease
prevention remain unclear. Objective To test whether vitamin D, omega-3s, and a strength …

Importance Preventive strategies for frailty are needed. Whether supplements with anti-
inflammatory properties, such as vitamin D 3 or marine omega-3 fatty acids, are useful for …

Background: Vitamin D insufficiency is prevalent among older adults and may be associated
with higher risk for cardiovascular (CV) disease, mortality, depression, and cognitive deficits …

Importance Vitamin D deficiency has been associated with poor physical performance.
Objective To determine the effectiveness of high-dose vitamin D in lowering the risk of …

This trial compared the effects of daily treatment with vitamin D or placebo for 1 year on
blood tests of vitamin D status. The results demonstrated that daily 4000 IU vitamin D3 is …

Objectives: To identify, appraise, and synthesize data from randomized, controlled trials of
vitamin D supplementation in older people. Design: A systematic review of trials identified …

Background. Vitamin D deficiency is common among older adults and is associated with
poor physical performance; however, studies examining longitudinal changes in 25 …

Background Vitamin D supplements are widely recommended for bone health in the general
population, but data on whether they prevent fractures have been inconsistent. Methods In …

Background The effect of vitamin D supplementation on muscle function in older adults has
been tested in randomized trials with mixed results, which may be due to differences in the …

Objectives: To study the effects of vitamin D supplementation in healthier populations of
men. Design: Randomized, controlled trial. Setting: General clinical research center …