Diversity of atopic dermatitis and selection of immune targets
C Rothenberg-Lausell, J Bar, E Del Duca… - Annals of Allergy …, 2023 - Elsevier
Atopic dermatitis (AD) is a heterogeneous immune-mediated skin disorder affecting people
of all ages and ethnicities. Despite the development of targeted therapeutics such as …
of all ages and ethnicities. Despite the development of targeted therapeutics such as …
Advances in atopic dermatitis in 2019-2020: Endotypes from skin barrier, ethnicity, properties of antigen, cytokine profiles, microbiome, and engagement of immune …
T Nomura, K Kabashima - Journal of Allergy and Clinical Immunology, 2021 - Elsevier
Key research advances in atopic dermatitis (AD) suggest the complexity of its endotypes. A
comprehensive serum biomarker panel revealed at least 4 types of AD. Some represent …
comprehensive serum biomarker panel revealed at least 4 types of AD. Some represent …
The translational revolution in atopic dermatitis: the paradigm shift from pathogenesis to treatment
P Facheris, J Jeffery, E Del Duca… - Cellular & Molecular …, 2023 - nature.com
Atopic dermatitis (AD) is the most common inflammatory skin disease, and it is considered a
complex and heterogeneous condition. Different phenotypes of AD, defined according to the …
complex and heterogeneous condition. Different phenotypes of AD, defined according to the …
Phenotypes and endotypes of atopic dermatitis: Clinical implications
M Kim, J Kim - Allergy, Asthma & Respiratory Disease, 2020 - synapse.koreamed.org
Atopic dermatitis (AD) is the most common chronic inflammatory skin disease, characterized
by a complex pathophysiology and a variety of clinical phenotypes. However …
by a complex pathophysiology and a variety of clinical phenotypes. However …
Skin barrier and immune dysregulation in atopic dermatitis: an evolving story with important clinical implications
T Czarnowicki, JG Krueger… - The Journal of Allergy and …, 2014 - Elsevier
Atopic dermatitis is the most common chronic inflammatory skin disease. Its pathogenesis
combines barrier defects, immune dysregulation, and increased skin infections; however …
combines barrier defects, immune dysregulation, and increased skin infections; however …
Immune pathways in atopic dermatitis, and definition of biomarkers through broad and targeted therapeutics
Y Mansouri, E Guttman-Yassky - Journal of Clinical Medicine, 2015 - mdpi.com
Atopic dermatitis (AD) is the most common inflammatory skin disease. Recent research
findings have provided an insight into the complex pathogenic mechanisms involved in this …
findings have provided an insight into the complex pathogenic mechanisms involved in this …
The immunology of atopic dermatitis and its reversibility with broad-spectrum and targeted therapies
PM Brunner, E Guttman-Yassky, DYM Leung - Journal of Allergy and …, 2017 - Elsevier
Atopic dermatitis (AD), the most common chronic inflammatory skin disease, is driven by
both terminal keratinocyte differentiation defects and strong type 2 immune responses. In …
both terminal keratinocyte differentiation defects and strong type 2 immune responses. In …
The evolving landscape of biologic therapies for atopic dermatitis: present and future perspective
Atopic dermatitis (AD) is one of the most common, chronic inflammatory skin diseases with a
significant physical, emotional and socioeconomic burden. In recent years the …
significant physical, emotional and socioeconomic burden. In recent years the …
Molecular mechanism–driven new biomarkers and therapies for atopic dermatitis
SS Mohapatra, S Mohapatra, AR McGill… - Journal of Allergy and …, 2020 - jacionline.org
The article by Lee at al 1 in this issue of the Journal of Allergy and Clinical Immunology
focuses on the role of IL-32g, an isotype of IL-32, in the development of atopic dermatitis …
focuses on the role of IL-32g, an isotype of IL-32, in the development of atopic dermatitis …
Immunopathogenesis of atopic dermatitis: focus on interleukins as disease drivers and therapeutic targets for novel treatments
K Makowska, J Nowaczyk, L Blicharz… - International Journal of …, 2023 - mdpi.com
Atopic dermatitis is a chronic, recurrent inflammatory skin disorder manifesting by
eczematous lesions and intense pruritus. Atopic dermatitis develops primarily as a result of …
eczematous lesions and intense pruritus. Atopic dermatitis develops primarily as a result of …
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