Heterochromatin remains condensed throughout the cell cycle, is generally transcriptionally
inert and is built and maintained by groups of factors with each group member sharing a …

Although heterochromatin has been studied for 80 years, its genetic function and molecular
organization have remained elusive. In almost all organisms, heterochromatin has been …

Heterochromatin is a key architectural feature of eukaryotic chromosomes, which endows
particular genomic domains with specific functional properties. The capacity of …

Heterochromatin is a key characteristic of eukaryotic genomes. Since its cytological
description nearly 100 years ago, our understanding of heterochromatin features and …

Significant portions of the eukaryotic genome are heterochromatic, made up largely of
repetitious sequences and possessing a distinctive chromatin structure associated with …

The large genomes of higher eukaryotes suggest a need for stable packaging, particularly
as most of the DNA does not code for proteins, and much consists of repetitious sequences …

Constitutive heterochromatin is composed mainly of repetitive elements and represents the
typical inert chromatin structure in eukaryotic cells. Approximately half of the mammalian …

The organization of chromosomes into euchromatin and heterochromatin is amongst the
most important and enigmatic aspects of genome evolution. Constitutive heterochromatin is …

All living organisms are constantly exposed to stresses from internal biological processes
and surrounding environments, which induce many adaptive changes in cellular physiology …

The eukaryotic genome is packaged into transcriptionally active euchromatin and silent
heterochromatin, with most studies focused on the former encompassing the majority of …