Diminished adult neurogenesis in the marmoset brain precedes old age

B Leuner, Y Kozorovitskiy… - Proceedings of the …, 2007 - National Acad Sciences
With aging there is a decline in the number of newly generated neurons in the dentate gyrus
of the hippocampus. In rodents and tree shrews, this age-related decrease in neurogenesis …

Production of new cells in the rat dentate gyrus over the lifespan: relation to cognitive decline

JL Bizon, M Gallagher - European Journal of Neuroscience, 2003 - Wiley Online Library
The identification of neurogenesis in the dentate gyrus of adult mammals has sparked much
interest in a functional role for these new neurons in hippocampal‐dependent cognition. The …

Neurogenesis decreases with age in the canine hippocampus and correlates with cognitive function

CT Siwak-Tapp, E Head, BA Muggenburg… - Neurobiology of learning …, 2007 - Elsevier
New neurons are continually produced in the adult mammalian brain from progenitor cells
located in specific brain regions, including the subgranular zone (SGZ) of the dentate gyrus …

Neurogenesis in a rat model of age‐related cognitive decline

JL Bizon, HJ Lee, M Gallagher - Aging cell, 2004 - Wiley Online Library
Age‐related decrements in hippocampal neurogenesis have been suggested as a basis for
learning impairment during aging. In the current study, a rodent model of age‐related …

Hippocampal neurogenesis in adult Old World primates

E Gould, AJ Reeves, M Fallah… - Proceedings of the …, 1999 - National Acad Sciences
The production of new hippocampal neurons in adulthood has been well documented in
rodents. Recent studies have extended these findings to other mammalian species, such as …

The window and mechanisms of major age‐related decline in the production of new neurons within the dentate gyrus of the hippocampus

MS Rao, B Hattiangady, AK Shetty - Aging cell, 2006 - Wiley Online Library
While it is well known that production of new neurons from neural stem/progenitor cells
(NSC) in the dentate gyrus (DG) diminishes greatly by middle age, the phases and …

Continuation of neurogenesis in the hippocampus of the adult macaque monkey

DR Kornack, P Rakic - … of the National Academy of Sciences, 1999 - National Acad Sciences
We present evidence for continuous generation of neurons, oligodendrocytes, and
astrocytes in the hippocampal dentate gyrus of adult macaque monkeys, using …

Mitotically active cells that generate neurons and astrocytes are present in multiple regions of the adult mouse hippocampus

R Rietze, P Poulin, S Weiss - Journal of Comparative …, 2000 - Wiley Online Library
Previous studies of the adult hippocampus of rodents and primates have reported neuro‐
and gliogenesis restricted to the region of the dentate gyrus. In the present study, by …

Effect of aging on neurogenesis in the canine brain

A Pekcec, W Baumgärtner, JP Bankstahl, VM Stein… - Aging …, 2008 - Wiley Online Library
An age‐dependent decline in hippocampal neurogenesis has been reported in laboratory
rodents. Environmental enrichment proved to be a strong trigger of neurogenesis in young …

Comparing adult hippocampal neurogenesis in mammalian species and orders: influence of chronological age and life history stage

I Amrein, K Isler, HP Lipp - European Journal of Neuroscience, 2011 - Wiley Online Library
Adult hippocampal neurogenesis is a prominent event in rodents. In species with longer life
expectancies, newly born cells in the adult dentate gyrus of the hippocampal formation are …