Nonsteroidal anti‐inflammatory therapy: a journey toward safety
C Pereira‐Leite, C Nunes, SK Jamal… - Medicinal research …, 2017 - Wiley Online Library
The efficacy of nonsteroidal anti‐inflammatory drugs (NSAIDs) against inflammation, pain,
and fever has been supporting their worldwide use in the treatment of painful conditions and …
and fever has been supporting their worldwide use in the treatment of painful conditions and …
Evolving therapeutic strategies to improve nonsteroidal anti-inflammatory drug safety
BH McCarberg, B Cryer - American journal of therapeutics, 2015 - journals.lww.com
Nonsteroidal anti-inflammatory drugs (NSAIDs) possess potent anti-inflammatory and
analgesic properties through inhibition of cyclooxygenase enzymes (COX-1 and COX-2) …
analgesic properties through inhibition of cyclooxygenase enzymes (COX-1 and COX-2) …
Nonsteroidal antiinflammatory drugs: past, present and future
Currently available NSAIDs represent a heterogeneous group of therapeutic agents
characterized by a variable benefit/risk profile. The development of a new class of selective …
characterized by a variable benefit/risk profile. The development of a new class of selective …
An evidence-based update on nonsteroidal anti-inflammatory drugs
CKS Ong, P Lirk, CH Tan… - Clinical medicine & …, 2007 - Marshfield Clinic
Nonsteroidal anti-inflammatory drugs (NSAIDs), including both traditional nonselective
NSAIDs and the selective cyclooxygenase (COX)-2 inhibitors, are widely used for their anti …
NSAIDs and the selective cyclooxygenase (COX)-2 inhibitors, are widely used for their anti …
Evolution of nonsteroidal anti-inflammatory drugs (NSAIDs): cyclooxygenase (COX) inhibition and beyond
P Rao, EE Knaus - Journal of pharmacy & …, 2008 - journals.library.ualberta.ca
Purpose. NSAIDs constitute an important class of drugs with therapeutic applications that
have spanned several centuries. Treatment of inflammatory conditions such as rheumatoid …
have spanned several centuries. Treatment of inflammatory conditions such as rheumatoid …
New insights into the use of currently available non-steroidal anti-inflammatory drugs
K Brune, P Patrignani - Journal of pain research, 2015 - Taylor & Francis
Non-steroidal anti-inflammatory drugs (NSAIDs), which act via inhibition of the
cyclooxygenase (COX) isozymes, were discovered more than 100 years ago. They remain a …
cyclooxygenase (COX) isozymes, were discovered more than 100 years ago. They remain a …
Selective COX-2 inhibitors and dual acting anti-inflammatory drugs: critical remarks
A Bertolini, A Ottani, M Sandrini - Current medicinal chemistry, 2002 - ingentaconnect.com
Non steroidal anti-inflammatory drugs (NSAIDs) are still the most commonly used remedies
for rheumatic diseases. But NSAIDs produce serious adverse effects, the most important …
for rheumatic diseases. But NSAIDs produce serious adverse effects, the most important …
Nonsteroidal anti-inflammatory drugs: a critical review on current concepts applied to reduce gastrointestinal toxicity
M Abdel-Tawab, H Zettl… - Current medicinal …, 2009 - ingentaconnect.com
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used drugs
worldwide. Nevertheless, their intake is frequently associated with gastrointestinal side …
worldwide. Nevertheless, their intake is frequently associated with gastrointestinal side …
Clinical pharmacology of non-steroidal anti-inflammatory drugs: a review
Non-steroidal anti-inflammatory drugs (NSAIDs) are a group of often chemically unrelated
compounds with some common therapeutic actions and side effects. They have potent anti …
compounds with some common therapeutic actions and side effects. They have potent anti …
NSAID induced gastrointestinal damage and designing GI-sparing NSAIDs
G García-Rayado, M Navarro… - Expert review of clinical …, 2018 - Taylor & Francis
NSAIDs are widely used to treat pain and rheumatic conditions, but they induce adverse
events in different body systems, although the major, most frequent events occur in the …
events in different body systems, although the major, most frequent events occur in the …