Functional Variant in the α2B Adrenoceptor Gene, a Positional Candidate on Chromosome 2, Associates With Hypertension
F Von Wowern, K Bengtsson, U Lindblad… - …, 2004 - Am Heart Assoc
In a genome-wide scan in Scandinavians, we found suggestive linkage between early-onset
primary hypertension and a region on chromosome 2. The α2B-adrenoceptor gene, a …
primary hypertension and a region on chromosome 2. The α2B-adrenoceptor gene, a …
Association of Hypertension with β2- and α2c10-Adrenergic Receptor Genotype
LP Svetkey, PZ Timmons, O Emovon, NB Anderson… - …, 1996 - Am Heart Assoc
The adrenergic receptors have been implicated in the pathogenesis of essential
hypertension. We hypothesized that hypertension is associated with variants at the β2 …
hypertension. We hypothesized that hypertension is associated with variants at the β2 …
An insertion/deletion polymorphism in the α2b-adrenergic receptor gene is a novel genetic risk factor for acute coronary events
A Snapir, P Heinonen, TP Tuomainen… - Journal of the American …, 2001 - jacc.org
OBJECTIVES Our aim was to study whether an insertion/deletion (I/D) polymorphism in the
α2B-adrenoceptor gene is associated with the risk for cardiovascular diseases …
α2B-adrenoceptor gene is associated with the risk for cardiovascular diseases …
Functional correlates of α2A-adrenoceptor gene polymorphism in the HANE study
MC Michel, C Plogmann, T Philipp… - Nephrology Dialysis …, 1999 - academic.oup.com
Background. The aim of this study was to test an association between alleles of the α 2A-
adrenoceptor gene with hereditary hypertension and with alterations of lipid and …
adrenoceptor gene with hereditary hypertension and with alterations of lipid and …
The insertion/deletion variation in the α2B-adrenoceptor does not seem to modify the risk for acute myocardial infarction, but may modify the risk for hypertension in …
A Snapir, M Scheinin, LC Groop… - Cardiovascular …, 2003 - Springer
Background An insertion/deletion polymorphism in the α 2B-adrenoceptor (AR) has been
associated with the risk for acute myocardial infarction (AMI) and sudden cardiac death. In …
associated with the risk for acute myocardial infarction (AMI) and sudden cardiac death. In …
β2 adrenoceptor functional gene variants, obesity, and blood pressure level interactions in the general population
AC Pereira, MS Floriano, GFA Mota, RS Cunha… - …, 2003 - Am Heart Assoc
We investigated the association of β2 adrenoceptor functional gene variants (Arg16Gly,
Gln27Glu, and Thr164Ile polymorphisms), obesity phenotypes, and blood pressure levels in …
Gln27Glu, and Thr164Ile polymorphisms), obesity phenotypes, and blood pressure levels in …
[HTML][HTML] β-2 adrenoceptor genetic variation is associated with genetic predisposition to essential hypertension: The Bergen Blood Pressure Study
β-2 Adrenoceptor genetic variation is associated with genetic predisposition to essential
hypertension: The Bergen Blood Pressure Study. We tested the hypothesis that genetic …
hypertension: The Bergen Blood Pressure Study. We tested the hypothesis that genetic …
Polymorphism in the β1-Adrenergic Receptor Gene and Hypertension
K Bengtsson, O Melander, M Orho-Melander… - Circulation, 2001 - Am Heart Assoc
Background—The Arg389 variant of the β1-adrenergic receptor gene mediates a higher
isoproterenol-stimulated adenylate cyclase activity than the Gly389 variant in vitro. We …
isoproterenol-stimulated adenylate cyclase activity than the Gly389 variant in vitro. We …
β2-adrenoceptor gene polymorphisms and blood pressure variations in East Anglian Caucasians
H Jia, P Sharma, R Hopper, C Dickerson… - Journal of …, 2000 - journals.lww.com
Objective The amino-terminal polymorphisms, Arg16Gly and Gln27Glu, of the β 2-
adrenergic receptor (β 2 AR) have been shown to affect regulation of the receptor …
adrenergic receptor (β 2 AR) have been shown to affect regulation of the receptor …
Alpha-and beta-adrenergic receptor polymorphisms in hypertensive and normotensive offspring
M Iacoviello, C Forleo, S Sorrentino… - Journal of …, 2006 - journals.lww.com
Background The offspring of hypertensive families are characterized by higher arterial blood
pressure values and a depressed autonomic control of heart rate. The present study aimed …
pressure values and a depressed autonomic control of heart rate. The present study aimed …