In a genome-wide scan in Scandinavians, we found suggestive linkage between early-onset
primary hypertension and a region on chromosome 2. The α2B-adrenoceptor gene, a …

The adrenergic receptors have been implicated in the pathogenesis of essential
hypertension. We hypothesized that hypertension is associated with variants at the β2 …

OBJECTIVES Our aim was to study whether an insertion/deletion (I/D) polymorphism in the
α2B-adrenoceptor gene is associated with the risk for cardiovascular diseases …

Background. The aim of this study was to test an association between alleles of the α 2A-
adrenoceptor gene with hereditary hypertension and with alterations of lipid and …

Background An insertion/deletion polymorphism in the α 2B-adrenoceptor (AR) has been
associated with the risk for acute myocardial infarction (AMI) and sudden cardiac death. In …

We investigated the association of β2 adrenoceptor functional gene variants (Arg16Gly,
Gln27Glu, and Thr164Ile polymorphisms), obesity phenotypes, and blood pressure levels in …

β-2 Adrenoceptor genetic variation is associated with genetic predisposition to essential
hypertension: The Bergen Blood Pressure Study. We tested the hypothesis that genetic …

Background—The Arg389 variant of the β1-adrenergic receptor gene mediates a higher
isoproterenol-stimulated adenylate cyclase activity than the Gly389 variant in vitro. We …

Objective The amino-terminal polymorphisms, Arg16Gly and Gln27Glu, of the β 2-
adrenergic receptor (β 2 AR) have been shown to affect regulation of the receptor …

Background The offspring of hypertensive families are characterized by higher arterial blood
pressure values and a depressed autonomic control of heart rate. The present study aimed …