Vaccination against Diphtheria & Pertussis has been a success story ever since its mass
usage since 1940. The dramatic reduction in both diseases witnessed globally still falls short …

Universal pertussis vaccination has successfully decreased pertussis mortality and morbidity
in childhood. However, despite intensive vaccination of young children, pertussis remains a …

Abstract Background. The Global Pertussis Initiative, an expert scientific forum, was
established to address the ongoing problems associated with pertussis disease worldwide …

Pertussis disease in infancy remains a significant problem, with a high risk of serious
morbidity and mortality in both developed and developing countries. Improved disease …

Pertussis is a serious disease for children in all countries, but it is more severe in the
developing world. Disease incidence, complication rates and case fatality rates are highest …

The introduction of pertussis vaccines and their subsequent widespread use globally have
resulted in a reduction in the incidence, morbidity and mortality of this disease. However …

Pertussis continues to be a significant cause of morbidity and mortality among
nonimmunized young infants. Although the inception of childhood pertussis immunization …

In the prevaccine era pertussis and diphtheria were responsible for significant morbidity and
mortality in children. In the United States of America more than 125,000 cases of diphtheria …

Pertussis is the only disease for which children are routinely vaccinated that is not at
historically low levels in the United States. The increases seen in pertussis are not due to …

Despite widespread immunization programs in most countries, pertussis disease continues
to be a threat to public health. In particular, there has been a resurgence of pertussis …