Currently, there is no effective therapy for chronic cerebral hypoperfusion-induced
subcortical ischemic vascular dementia (SIVD), which displays cognitive deficits and …

Subcortical ischemic vascular dementia (SIVD), which is caused by chronic cerebral
hypoperfusion, is a common subtype of vascular dementia, accompanied by white matter …

Neuroinflammation is considered as an important mechanism of vascular dementia (VaD).
Our primary study showed that the bisindole analogue (2-(2-(bis (5-chloro-1H-indol-3-yl) …

Background: Chronic cerebral hypoperfusion has been well-characterized as a common
pathological status contributing to vascular dementia (VD). In this study, the neuroprotective …

Radix Angelica Sinensis (RAS) has beneficial effects in patients suffering from cognitive
impairment associated with chronic cerebral hypoperfusion. It has previously been …

Demyelination in vascular dementia (VD) is partly attributable to inflammation induced by
chronic cerebral hypoperfusion (CCH). Remyelination contributes to the recovery of …

Vascular cognitive impairment caused by chronic cerebral hypoperfusion (CCH) seriously
affects the quality of life of elderly patients and places a great burden on society and family …

Vascular dementia is a neurodegenerative disorder caused by the reduction of cerebral
blood flow. It shows a progressive cognitive impairment. In our previous study, we found that …

Vascular dementia (VaD) is the second reason for the cognitive decline in aged people, but
the effective therapy is still missing. The chronic cerebral hypoperfusion (CCH) had been …

Chronic cerebral hypoperfusion is an important risk factor for vascular dementia (VaD) and
other brain dysfunctions, for which there are currently no effective medications available. In …