OSCAR is a receptor for surfactant protein D that activates TNF-α release from human CCR2+ inflammatory monocytes
AD Barrow, Y Palarasah, M Bugatti… - The Journal of …, 2015 - journals.aai.org
Abstract Surfactant protein D (SP-D) is critical for maintenance of lung homeostasis and
provides a first line of defense to pathogens at mucosal surfaces. Polymorphisms in the SP …
provides a first line of defense to pathogens at mucosal surfaces. Polymorphisms in the SP …
Surfactant protein D regulates airway function and allergic inflammation through modulation of macrophage function
K Takeda, N Miyahara, YH Rha, C Taube… - American journal of …, 2003 - atsjournals.org
The lung collectin surfactant protein D (SP-D) is an important component of the innate
immune response but is also believed to play a role in other regulatory aspects of immune …
immune response but is also believed to play a role in other regulatory aspects of immune …
[HTML][HTML] Pulmonary surfactant protein D inhibits lipopolysaccharide (LPS)-induced inflammatory cell responses by altering LPS binding to its receptors
M Yamazoe, C Nishitani, M Takahashi, T Katoh… - Journal of biological …, 2008 - ASBMB
Pulmonary surfactant protein D (SP-D) is a member of the collectin family that plays an
important role in regulating innate immunity of the lung. We examined the mechanisms by …
important role in regulating innate immunity of the lung. We examined the mechanisms by …
A common polymorphism in the SFTPD gene influences assembly, function, and concentration of surfactant protein D
R Leth-Larsen, P Garred, H Jensenius… - The Journal of …, 2005 - journals.aai.org
Abstract Surfactant protein D (SP-D) plays important roles in the host defense against
infectious microorganisms and in regulating the innate immune response to a variety of …
infectious microorganisms and in regulating the innate immune response to a variety of …
Polymorphisms in surfactant protein–D are associated with chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is characterized by alveolar destruction and
abnormal inflammatory responses to noxious stimuli. Surfactant protein–D (SFTPD) is …
abnormal inflammatory responses to noxious stimuli. Surfactant protein–D (SFTPD) is …
[HTML][HTML] Surfactant protein D in respiratory and non-respiratory diseases
GL Sorensen - Frontiers in medicine, 2018 - frontiersin.org
Surfactant protein D (SP-D) is a multimeric collectin that is involved in innate immune
defense and expressed in pulmonary, as well as non-pulmonary, epithelia. SP-D exerts …
defense and expressed in pulmonary, as well as non-pulmonary, epithelia. SP-D exerts …
Neither SP-A nor NH2-terminal domains of SP-A can substitute for SP-D in regulation of alveolar homeostasis
L Zhang, M Ikegami, TR Korfhagen… - … of Physiology-Lung …, 2006 - journals.physiology.org
Surfactant proteins (SP)-A and-D are members of the collectin family of host defense
proteins that share four distinct structural domains: NH2-terminal oligomerization …
proteins that share four distinct structural domains: NH2-terminal oligomerization …
[HTML][HTML] Correction of pulmonary abnormalities in Sftpd-/-mice requires the collagenous domain of surfactant protein D
PS Kingma, L Zhang, M Ikegami, K Hartshorn… - Journal of Biological …, 2006 - ASBMB
Surfactant protein D (SP-D) is a member of the collectin family of innate defense proteins.
Members of this family share four distinct structural domains: an N-terminal cross-linking …
Members of this family share four distinct structural domains: an N-terminal cross-linking …
[HTML][HTML] Surfactant protein-D and pulmonary host defense
EC Crouch - Respiratory research, 2000 - Springer
Abstract Surfactant protein-D (SP-D) participates in the innate response to inhaled
microorganisms and organic antigens, and contributes to immune and inflammatory …
microorganisms and organic antigens, and contributes to immune and inflammatory …
[HTML][HTML] Chronic obstructive pulmonary disease and inhaled steroids alter surfactant protein D (SP-D) levels: a cross-sectional study
MW Sims, RM Tal-Singer, S Kierstein, AI Musani… - Respiratory …, 2008 - Springer
Abstract Background Surfactant protein D (SP-D), an innate immune molecule, plays an
important protective role during airway inflammation. Deficiency of this molecule induces …
important protective role during airway inflammation. Deficiency of this molecule induces …
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