Pharmaceutical companies have a continuous need to resolve new racemates. Analysis
may be required in aqueous and nonaqueous media, or in the presence of several different …

Abstract Derivatives of 2-amino-2-deoxyglucose covalently connected to aminopropyl-silica
gel were used as chiral selectors in the separation of racemic pharmaceuticals. β-Receptor …

Mixtures of hexane-like ethoxynonafluorobutane with alcohols were used as MS-friendly
mobile phases for separation and efficient detection of non-UV-active enantiomers and …

The preparative chromatographic resolution of racemates has become a standard approach
for the generation of enantiomers in pharmaceutical discovery laboratories. This paper will …

Many drugs are recemic and therefore much effort has to be devoted towards the
stereoselective synthesis of the most effective or less harmful component of a racemic …

Racemates are fixed-dose combinations of stereoisomers. Each isomer may have different
pharmacokinetic or pharmacodynamic properties. Recent research has allowed …

Enantiomeric separation of mosapride and a structurally related compound was performed
using chiral chromatography and experimental design. Unique effects of mobile phase pH …

Scientists have been interested in optically active compounds ever since Pasteur (1)
reported the resolution of racemic sodium ammonium tartrate into its enantiomorphs …

The potential of contemporary chiral liquid chromatographic columns for the
enantioseparation of racemates of pharmaceutical compounds was studied. Sixteen …