Start a fire, kill the bug: The role of platelets in inflammation and infection

C Deppermann, P Kubes - Innate immunity, 2018 - journals.sagepub.com
Platelets are the main players in thrombosis and hemostasis; however they also play
important roles during inflammation and infection. Through their surface receptors, platelets …

Platelets in inflammation and infection

CN Jenne, P Kubes - Platelets, 2015 - Taylor & Francis
Although platelets are traditionally recognized for their central role in hemostasis, many lines
of research clearly demonstrate these rather ubiquitous blood components are potent …

Emerging roles for platelets as immune and inflammatory cells

CN Morrell, AA Aggrey, LM Chapman… - Blood, The Journal of …, 2014 - ashpublications.org
Despite their small size and anucleate status, platelets have diverse roles in vascular
biology. Not only are platelets the cellular mediator of thrombosis, but platelets are also …

Regulation of innate immune responses by platelets

LS Ribeiro, L Migliari Branco, BS Franklin - Frontiers in immunology, 2019 - frontiersin.org
The role of platelets has been extensively studied in the context of coagulation and vascular
integrity. Their hemostatic imbalance can lead to known conditions as atherosclerotic …

[HTML][HTML] Platelets in inflammation and immunity

JM Herter, J Rossaint, A Zarbock - Journal of Thrombosis and Haemostasis, 2014 - Elsevier
The paradigm of platelets as mere mediators of hemostasis has long since been replaced by
a dual role: hemostasis and inflammation. Now recognized as key players in innate and …

Platelets in the NETworks interweaving inflammation and thrombosis

AK Wienkamp, L Erpenbeck, J Rossaint - Frontiers in Immunology, 2022 - frontiersin.org
Platelets are well characterized for their indispensable role in primary hemostasis to control
hemorrhage. Research over the past years has provided a substantial body of evidence …

Platelets as key players in inflammation and infection

L Nicolai, S Massberg - Current opinion in hematology, 2020 - journals.lww.com
New findings highlight the complex interplay of innate immunity, coagulation and platelets in
inflammation and infection, and unravel novel molecular pathways and effector functions …

Crosstalk between platelets and microbial pathogens

C Li, J Li, H Ni - Frontiers in immunology, 2020 - frontiersin.org
Platelets, small anucleate cells circulating in the blood, are critical mediators in haemostasis
and thrombosis. Interestingly, recent studies demonstrated that platelets contain both pro …

Platelets: bridging hemostasis, inflammation, and immunity

CN Jenne, R Urrutia, P Kubes - International journal of …, 2013 - Wiley Online Library
Although the function of platelets in the maintenance of hemostasis has been studied in
great detail, more recent evidence has highlighted a central role for platelets in the host …

Platelets as modulators of inflammation

SJ Kim, RP Davis, CN Jenne - Seminars in Thrombosis and …, 2018 - thieme-connect.com
Platelets have classically been considered crucial effector cells in hemostasis, but now are
increasingly recognized as players during inflammatory responses in innate and adaptive …