[HTML][HTML] Endothelial progenitor cells promote osteosarcoma progression and invasiveness via AKT/PI3K signaling

O Doppelt-Flikshtain, A Younis, T Tamari, O Ginesin… - Cancers, 2023 - mdpi.com
Simple Summary Although progress has been made in the treatment and survival of patients
with a range of malignancies, the prognosis for patients harboring metastatic osteosarcoma …

Bone marrow-derived endothelial progenitor cells contribute to the angiogenic switch in tumor growth and metastatic progression

D Gao, D Nolan, K McDonnell, L Vahdat… - … et Biophysica Acta (BBA …, 2009 - Elsevier
Emerging evidence indicates that bone marrow (BM)-derived endothelial progenitor cells
(EPCs) contribute to angiogenesis-mediated growth of certain tumors in mice and human …

[HTML][HTML] A review into the insights of the role of endothelial progenitor cells on bone biology

H Shi, Z Zhao, W Jiang, P Zhu, N Zhou… - Frontiers in Cell and …, 2022 - frontiersin.org
In addition to its important transport functions, the skeletal system is involved in complex
biological activities for the regulation of blood vessels. Endothelial progenitor cells (EPCs) …

Co-culture with endothelial progenitor cells promotes survival, migration, and differentiation of osteoclast precursors

H Pang, XH Wu, SL Fu, F Luo, ZH Zhang… - Biochemical and …, 2013 - Elsevier
In this study, we report the effect of endothelial progenitor cells (EPCs) on the biological
behavior of osteoclast precursors in vitro by establishing an indirect co-culture system of …

[HTML][HTML] Monocytes as endothelial progenitor cells (EPCs), another brick in the wall to disentangle tumor angiogenesis

F Lopes-Coelho, F Silva, S Gouveia-Fernandes… - Cells, 2020 - mdpi.com
Bone marrow contains endothelial progenitor cells (EPCs) that, upon pro-angiogenic stimuli,
migrate and differentiate into endothelial cells (ECs) and contribute to re-endothelialization …

Cell trafficking of endothelial progenitor cells in tumor progression

P De La Puente, B Muz, F Azab, AK Azab - Clinical Cancer Research, 2013 - AACR
Blood vessel formation plays an essential role in many physiologic and pathologic
processes, including normal tissue growth and healing, as well as tumor progression …

Therapeutic potential of endothelial progenitor cells in the field of orthopaedics

Y Kawakami, T Matsumoto, Y Mifune… - Current Stem Cell …, 2017 - ingentaconnect.com
Inadequate blood supply frequently impedes the viability of tissue-engineered constructs in
the initial phase after implantation, and can lead to improper cell integration or cell death …

[HTML][HTML] Endothelial progenitor cells enhance the migration and osteoclastic differentiation of bone marrow-derived macrophages in vitro and in a mouse femur …

Y Cui, S Fu, T Hou, X Wu - Cellular Physiology and Biochemistry, 2018 - karger.com
Background/Aims: Bone resorption mediated by osteoclasts plays an important role in bone
healing. Endothelial progenitor cells (EPCs) promote bone repair by stimulating …

[HTML][HTML] Endothelial progenitor cells promote tumor growth and progression by enhancing new vessel formation

X Zhao, HQ Liu, J Li, XL Liu - Oncology letters, 2016 - spandidos-publications.com
Tumor growth and progression require new blood vessel formation to deliver nutrients and
oxygen for further cell proliferation and to create a neovascular network exit for tumor cell …

Circulating endothelial/skeletal progenitor cells for bone regeneration and healing

T Matsumoto, R Kuroda, Y Mifune, A Kawamoto… - Bone, 2008 - Elsevier
An emerging strategy in the regeneration and repair of bone is to use stem cells, including
bone marrow mesenchymal stem cells, which are the most investigated and reliable source …