Post-sepsis early mortality is being replaced by survivors who experience either a rapid
recovery and favorable hospital discharge or the development of chronic critical illness (CCI) …

Surgical sepsis has evolved into two major subpopulations: patients who rapidly recover,
and those who develop chronic critical illness (CCI). Our primary aim was to determine …

The still raging SARS-CoV-2/COVID-19 pandemic has understandably diverted the research
attention from other important domains of medical sciences. This Research Topic partly fills …

Background With the successful implementation of the Surviving Sepsis Campaign
guidelines, post-sepsis in-hospital mortality to sepsis continues to decrease. Those who …

Sepsis is a highly prevalent cause of death in intensive care units. Characterized by severe
immune cell derangements, sepsis is often associated with multiorgan dysfunction. For …

Objectives: Sepsis and trauma are common health problems and provide great challenges
in critical care. Diverse patient responses to these conditions further complicate patient …

Systemic infections, especially in patients with chronic diseases, may result in sepsis: an
explosive, uncoordinated immune response that can lead to multisystem organ failure with a …

A complicated clinical course for critically ill patients admitted to the intensive care unit (ICU)
usually includes multiorgan dysfunction and subsequent death. Owing to the heterogeneity …

Introduction & Rationale: To identify whole blood transcripts that are differentially expressed
between patients with septic shock compared to those critically ill with sepsis but without …

Background There are diverse molecules present in blood plasma that regulate immune
functions and also present a potential source of disease biomarkers and therapeutic targets …