Various drugs are not able to reach the market due to their poor bioavailability and poor
solubility in aqueous media. Hence, several approaches are used to enhance the solubility …

The concept of Co-crystallization discovered almost a century ago, but it has inspired a great
interest of researchers in modern day due to their ability to improve physical properties of …

Pharmaceutical co-crystals have conferred significant recognition in recent past as a new
solid form by virtue their capability to modulate physicochemical properties of Active …

Low aqueous solubility and concomitant oral bioavailability are the major glitches found in
converting the active pharmaceutical ingredients to new pharmaceutical products. Many …

Poor drug solubility with the consequent low bioavailability represents one of the main
obstacles to the introduction of new drugs into the market. Several approaches were tried to …

Co-crystals consists of API and a stoichiometric amount of a pharmaceutically acceptable co-
crystal former. Pharmaceutical Co-crystals are nonionic supramolecular complexes and can …

The issue of poor aqueous solubility is a major hurdle in pharmaceutical dosage form
design. A large number of active molecules in the research and development pipeline …

The oral drug delivery is widely used and accepted routes of administration, but it fails to
provide the therapeutic effectiveness of drugs due to low solubility, poor compression and …

Pharmaceutical co-crystals have gained significant attention in recent years as a promising
green and sustainable method for poorly soluble drugs to improve their solubility, stability …

A review on pharmaceutical co-crystals, nutraceutical co-crystals and pharmaceutical co-
crystal polymorphs depicting their relevance both in academia and pharmaceutical industry …