To develop potent and environment-friendly insecticides, novel N-pyridylpyrazole amide
derivatives containing a phthalimide were designed and synthesized. The preliminary …

To cope with the global food shortage and insect pest, there is an urgent need to discover
new pesticides with novel modes of actions. Ryanodine receptor (RyR) insecticides showed …

Insect ryanodine receptor is one of the promising targets for the development of novel
insecticides. In order to search for potent insecticides targeting the ryanodine receptor …

BACKGROUND Anthranilic diamide insecticides control lepidopteran pests through
selectively binding and activating insect ryanodine receptors. In order to search for potential …

Pests are one of the major factors causing crop damage and food security problems
worldwide. Based on our previous studies on the discovery of insecticidal leads targeting the …

To develop the novel ryanodine receptors (RyRs) insecticides, encouraged by our previous
research work, a series of novel N-phenylpyrazole derivatives containing a polysubstituted …

To discover potent insecticides targeting ryanodine receptors (RyRs), a series of novel
anthranilic diamides analogues (12a–12u) containing N-substituted phenylpyrazole were …

In order to search for the new ryanodine receptor (RyR) regulator, a series of 35 novel fluoro-
substituted compounds introduced 1-(2-chloro-4, 5-difluorophenyl)-1H-pyrazole moiety …

In order to look for novel insecticides targeting the ryanodine receptor, four new series of
anthranilic diamides containing modified N-pyridylpyrazoles were designed and …

The diamide insecticides show exceptional activity against Lepidoptera insects via activation
of ryanodine receptors (RyRs). In the present study, a series of anthranilic diamides …