Clinical trials show that insulin administered intranasally is a promising drug to treat
neurodegenerative diseases, but at high doses its use may result in cerebral insulin …

The aim of the present work is to study the mechanism of the α-tocopherol (α-T) protective
action at nanomolar and micromolar concentrations against H2O2-induced brain cortical …

Oxidative stress due to increased free radical generation and depletion of endogenous
antioxidants have been implicated in ischemia–reperfusion‐induced neuronal injury. The …

α‐tocopherol pretreatment alleviates cerebral ischemia‐reperfusion injury in rats - PMC Back to
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It has been recently shown that insulin has a neuroprotective effect. Experimental studies
and clinical trials have demonstrated that insulin is a promising drug for treatment of …

Diabetes mellitus is a risk factor for cerebrovascular ischemic disease. Aspirin
(acetylsalicylic acid) is the most widely used drug for the secondary prevention of thrombotic …

DOI: 10.1134/S0022093019040094 were shown to cause severe hypoglycemia and thus
have varied, including negative, effects [2]. However, studies of the protective effect of …

Clinical trials of insulin and experiments on its intranasal administration to animals suggest
that this hormone can be efficient in treating human neurodegenerative and some other …

Insulin is a promising drug for the treatment of diseases associated with brain damage.
However, the mechanism of its neuroprotective action is far from being understood. Our aim …

Background: Reduced cerebral blood flow is associated with aging, neurodegenerative
disorders, and an increased formation of reactive oxygen species. This study was designed …