Although decades of the reductionist approach achieved great milestones in optimizing the
immunosuppression therapy, traditional clinical parameters still fail in predicting both acute …

High throughput, high density platforms for transcriptional, proteomic, and metabonomic
analyses are opening new doors for improving our understanding of the complexity and …

Attaining a fair long-term allograft survival remains a challenge for allogeneic transplantation
worldwide. Although the emergence of immunosuppressants has caused noticeable …

Novel biomarkers of allograft rejection: ‘omics’ approaches... : Current Opinion in Organ
Transplantation Novel biomarkers of allograft rejection: ‘omics’ approaches start to deliver …

The translation of potential biomarkers from the laboratory bench to the clinical bedside is
not an easy task and will require the concerted effort of the immunologists, molecular …

For most patients with end-stage heart failure, heart transplantation is the treatment of
choice. Allograft rejection is one of the major post-transplantation complications affecting …

Although current regimens of immunosuppressive drugs are effective in renal transplant
recipients, long-term renal allograft outcomes remain suboptimal. For many years, the …

Multi-omics research is a key ingredient of data-intensive life sciences research, permitting
measurement of biological molecules at different functional levels in the same individual. For …

Introduction: Identification of allograft injury, including acute clinical and subclinical injury, is
vital in increasing the longevity of the transplanted organ. Acute rejection, which occurs as a …

Technological advances in molecular and in silico research have enabled significant
progress towards personalized transplantation medicine. It is now possible to conduct …