Adhesion and Invasion of Gastric Mucosa Epithelial Cells by Helicobacter pylori

Y Huang, Q Wang, D Cheng, W Xu… - Frontiers in cellular and …, 2016 - frontiersin.org
Helicobacter pylori is the main pathogenic bacterium involved in chronic gastritis and peptic
ulcer and a class 1 carcinogen in gastric cancer. Current research focuses on the …

[HTML][HTML] Effect of Helicobacter pylori on gastric epithelial cells

S Alzahrani, TT Lina, J Gonzalez… - World journal of …, 2014 - ncbi.nlm.nih.gov
The gastrointestinal epithelium has cells with features that make them a powerful line of
defense in innate mucosal immunity. Features that allow gastrointestinal epithelial cells to …

Helicobacter pylori: an invading microorganism? A review

AM Petersen, KA Krogfelt - FEMS Immunology & Medical …, 2003 - academic.oup.com
In this review we evaluate the pros and cons of Helicobacter pylori invasion of epithelial
cells as part of the natural history of H. pylori infection. H. pylori is generally considered an …

Invasion and Multiplication of Helicobacter pylori in Gastric Epithelial Cells and Implications for Antibiotic Resistance

YT Chu, YH Wang, JJ Wu, HY Lei - Infection and immunity, 2010 - Am Soc Microbiol
Helicobacter pylori is a Gram-negative, spiral-shaped bacterium that infects more than 50%
of the human population and can cause gastritis, peptic ulcer, or gastric malignancies. It is …

Helicobacter pylori colonization of the human gastric epithelium: A bug's first step is a novel target for us

BS Sheu, HB Yang, YC Yeh… - Journal of gastroenterology …, 2010 - Wiley Online Library
After Helicobacter pylori enters the stomach, three steps are vital for infection:(i) establishing
colonization;(ii) evading host immunity; and (iii) invading gastric mucosa; the last step is …

"Targeted disruption of the epithelial-barrier by Helicobacter pylori"

LE Wroblewski, RM Peek - Cell Communication and Signaling, 2011 - Springer
Helicobacter pylori colonizes the human gastric epithelium and induces chronic gastritis,
which can lead to gastric cancer. Through cell-cell contacts the gastric epithelium forms a …

[PDF][PDF] Helicobacter pylori and gastric epithelial cells: from gastritis to cancer

R Penta, M De Falco, G Iaquinto… - Journal of Experimental …, 2005 - academia.edu
Helicobacter pylori is a spiral, gram-negative rod-shaped pathogen that attaches to gastric
epithelial cells in the human stomach and is a causative agent of chronic active gastritis …

Molecular Mechanisms of Helicobacter pylori Pathogenesis

M De Falco, A Lucariello, S Iaquinto… - Journal of cellular …, 2015 - Wiley Online Library
Helicobacter pylori infects 50% of mankind. The vast majority of H. pylori infection occurs in
the developing countries where up to 80% of the middle‐aged adults may be infected …

[HTML][HTML] Adherens junctions as targets of microorganisms: a focus on Helicobacter pylori

AM Costa, M Leite, R Seruca, C Figueiredo - FEBS letters, 2013 - Elsevier
Mucosal epithelia are targeted by several microorganisms as a way of adhesion,
internalization, and/or exploitation of the host properties to induce disease. Helicobacter …

Helicobacter pylori Entry into Human Gastric Epithelial Cells: A Potential Determinant of Virulence, Persistence, and Treatment Failures 1

B Björkholm, V Zhukhovitsky, C Löfman, K Hultén… - …, 2000 - Wiley Online Library
Background and Objectives. Intracellular location of Helicobacter pylori in human gastric
epithelial cells has been observed in biopsies. Whether this reflects an ability to invade host …