Delayed fracture healing is the improper healing of fractures within a reasonable amount of
time and is estimated to impact a sixth of all fractures that occur annually in the United …

Successful clinical management of fracture repair requires an understanding of repair
biology, advantages and limitations of current fixation methods, and feasibility of and …

Bone scaffolds in tissue engineering are used to provide mechanical support and facilitate
bone regeneration. For this, mechanical and mass transport properties are of critical …

Large bone defects are clinically challenging, with up to 15% of these requiring surgical
intervention due to non-union. Bone grafts (autographs or allografts) can be used but they …

Abstract 3D printed bone scaffolds have the potential to replace autografts and allografts
because of advantages such as unlimited supply and the ability to tailor the scaffolds' …

Simple Summary This study aimed at producing a polymeric scaffold with the ability to
replicate the structure and mechanical properties of native trabecular bone. The scaffold's …

The treatment of large segmental bone defects remains a significant clinical challenge. Due
to limitations surrounding the use of bone grafts, tissue-engineered constructs for the repair …

Bone is a complex connective tissue that serves as mechanical and structural support for the
human body. Bones' fractures are common, and the healing process is physiologically …

Computational approaches have great potential for aiding clinical product development by
finding promising candidate designs prior to expensive testing and clinical trials. Here, an …

Additively manufactured synthetic bone scaffolds have emerged as promising candidates for
the replacement and regeneration of damaged and diseased bones. By employing optimal …