FGF23 Expression Is a Promising Immunohistochemical Diagnostic Marker for Undifferentiated Pleomorphic Sarcoma of Bone (UPSb)

HO Al-Hassi, NM Ali, H Cooke, S De Silva, AT Brini… - Genes, 2024 - mdpi.com
Background: Undifferentiated pleomorphic sarcoma of bone (UPSb) is a rare primary bone
sarcoma that lacks a specific line of differentiation. Distinguishing between UPSb and other …

[HTML][HTML] Immunohistochemical and molecular detection of the expression of FGF23 in phosphaturic mesenchymal tumors including the non-phosphaturic variant

E Shiba, A Matsuyama, R Shibuya, K Yabuki… - Diagnostic …, 2016 - Springer
Abstract Background Phosphaturic mesenchymal tumors (PMTs) are rare neoplasms that
are often associated with tumor-induced osteomalacia (TIO) due to excessive serum levels …

Genomic and transcriptomic characterisation of undifferentiated pleomorphic sarcoma of bone

NM Ali, S Niada, AT Brini, MR Morris… - The Journal of …, 2019 - Wiley Online Library
Undifferentiated pleomorphic sarcoma of bone (UPSb) is a rare primary bone sarcoma that
lacks a specific line of differentiation. There is very little information about the genetic …

A novel chromogenic in situ hybridization assay for FGF23 mRNA in phosphaturic mesenchymal tumors

JM Carter, BL Caron, A Dogan… - The American journal of …, 2015 - journals.lww.com
Phosphaturic mesenchymal tumors of the mixed connective tissue type (PMT) are very rare
tumors of bone and soft tissues. Most patients with PMT have long-standing osteomalacia …

Pathology of pleomorphic/undifferentiated and dedifferentiated bone neoplasms

I Brčić, AE Rosenberg - Seminars in diagnostic pathology, 2021 - Elsevier
Primary malignant bone tumors are uncommon and their accurate classification requires
careful correlation of clinical, radiological, and pathologic findings. It is a heterogeneous …

Consistent amplification of FRS2 and MDM2 in low-grade osteosarcoma: a genetic study of 22 cases with clinicopathologic analysis

X He, Z Pang, X Zhang, T Lan, H Chen… - The American Journal …, 2018 - journals.lww.com
Low-grade osteosarcoma (LGOS) encompasses low-grade central osteosarcoma (LGCOS)
and parosteal osteosarcoma (POS). LGOSs are characterized by a supernumerary ring and …

Array comparative genomic hybridization reveals frequent alterations of G1/S checkpoint genes in undifferentiated pleomorphic sarcoma of bone

T Niini, L Lahti, F Michelacci, S Ninomiya… - Genes …, 2011 - Wiley Online Library
Undifferentiated pleomorphic sarcoma of bone (UPSb) is a rare tumor often difficult to
differentiate from fibrosarcoma of bone (FSb), diagnostically. We applied array comparative …

[HTML][HTML] Basic fibroblast growth factor autocrine loop controls human osteosarcoma phenotyping and differentiation

M Bodo, C Lilli, C Bellucci, P Carinci, M Calvitti… - Molecular …, 2002 - Springer
Background We focused on the phenotype of non-mineralizing MG63 and mineralizing
TE85 human osteosarcoma cells and investigated the role of bFGF in modulating their …

P36. The role of FGF-signalling in osteosarcoma: A potential therapeutic target?

D Weekes, T Kashima… - Cancer Treatment …, 2008 - cancertreatmentreviews.com
Osteosarcoma (OS) is the most common human primary skeletal malignancy. However,
current treatment strategies rely heavily on surgical intervention and there are no curative …

Genetic analysis of fibrosarcoma of bone, a rare tumour entity closely related to osteosarcoma and malignant fibrous histiocytoma of bone

CM Hattinger, M Tarkkanen, S Benini, M Pasello… - European journal of cell …, 2004 - Elsevier
Fibrosarcoma (FS) of bone is an extremely rare and genetically uncharacterised malignant
tumour arising in the skeleton. On the basis of clinicopathologic features it appears to be …