The Wnt signaling pathway plays a role in the development of the central nervous system
and growing evidence indicates that Wnts also regulates the structure and function of the …

The roles of the Wnt signalling pathway in several developmental processes, including
synaptic differentiation, are well characterized. The expression of Wnt ligands and Wnt …

During development of the central nervous system the Wnt signaling pathway has been
implicated in a wide spectrum of physiological processes, including neuronal connectivity …

Ever since their discoveries, the Wnt pathways have been consistently associated with key
features of cellular development, including metabolism, structure and cell fate. The three …

Wnt components are key regulators of a variety of developmental processes, including
embryonic patterning, cell specification, and cell polarity. The Wnt signaling pathway …

Wnts are secreted glycoproteins that play multiple roles in early development, including the
differentiation of precursor cells. During this period, gradients of Wnts and other morphogens …

Neurogenesis persists during adulthood in the dentate gyrus of the hippocampus. Signals
provided by the local hippocampal microenvironment support neural stem cell proliferation …

Wnts comprise a large family of proteins that have shown to be part of a signaling cascade
that regulates several aspects of development including organogenesis, midbrain …

In the adult brain new neurons are continuously generated mainly in two regions, the
subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) in the …

Wnts are a highly conserved family of secreted glycoproteins that play essential roles in the
morphogenesis and body patterning during the development of metazoan species. In recent …