[HTML][HTML] Understanding the role of oxidative stress, neuroinflammation and abnormal myelination in excessive aggression associated with depression: recent input …

A Gorlova, E Svirin, D Pavlov, R Cespuglio… - International journal of …, 2023 - mdpi.com
Aggression and deficient cognitive control problems are widespread in psychiatric disorders,
including major depressive disorder (MDD). These abnormalities are known to contribute …

Role of oxidative stress in depression

S Bhatt, AN Nagappa, CR Patil - Drug discovery today, 2020 - Elsevier
Highlights•The Reactive Oxygen Species have an utmost importance in progression of
Depression.•Depression is associated with lowered concentration of anti-oxidants in …

Clinical and biochemical manifestations of depression: relation to the neurobiology of stress

PW Gold, R Machado-Vieira, MG Pavlatou - Neural plasticity, 2015 - Wiley Online Library
Major depressive disorder (MDD) is a chronic, recurrent, and severe psychiatric disorder
with high mortality and medical comorbidities. Stress‐related pathways have been directly …

[HTML][HTML] Exploring the role of inflammation in major depressive disorder: beyond the monoamine hypothesis

I Pastis, MG Santos, A Paruchuri - Frontiers in Behavioral …, 2024 - frontiersin.org
Major depressive disorder affects approximately 8.4% of the United States population. The
World Health Organization estimates that 280 million adults worldwide are suffering from …

[HTML][HTML] Oxidative stress in depression: the link with the stress response, neuroinflammation, serotonin, neurogenesis and synaptic plasticity

AS Correia, A Cardoso, N Vale - Antioxidants, 2023 - mdpi.com
Depression is a prevalent, complex, and highly debilitating disease. The full comprehension
of this disease is still a global challenge. Indeed, relapse, recurrency, and therapeutic …

Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a …

B Leonard, M Maes - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
This paper reviews that cell-mediated-immune (CMI) activation and inflammation contribute
to depressive symptoms, including anhedonia; anxiety-like behaviors; fatigue and somatic …

[HTML][HTML] Inflammatory depression—mechanisms and non-pharmacological interventions

K Suneson, J Lindahl, S Chamli Hårsmar… - International journal of …, 2021 - mdpi.com
Treatment of depression is hampered by the failure to identify distinct symptom profiles with
distinct pathophysiologies that differentially respond to distinct treatments. We posit that …

How oxidative stress induces depression?

N Ji, M Lei, Y Chen, S Tian, C Li, B Zhang - ASN neuro, 2023 - journals.sagepub.com
Depression increasingly affects a wide range and a large number of people worldwide, both
physically and psychologically, which makes it a social problem requiring prompt attention …

[HTML][HTML] Current understanding of the bi-directional relationship of major depression with inflammation

B Messay, A Lim, AL Marsland - Biology of mood & anxiety disorders, 2012 - Springer
Consistent evidence links major depression and its affective components to negative health
outcomes. Although the pathways of these effects are likely complex and multifactorial …

The effects of psychological stress on depression

L Yang, Y Zhao, Y Wang, L Liu… - Current …, 2015 - ingentaconnect.com
Major depressive disorder is a serious mental disorder that profoundly affects an individual's
quality of life. Although the aetiologies underlying this disorder remain unclear, an …