Yersinia are gram-negative zoonotic bacteria that use a type three secretion system (T3SS)
to inject Yersinia outer proteins (Yops) into the host cytosol in order to subvert essential …

Yersinia are gram-negative zoonotic bacteria that use a type III secretion system (T3SS) to
inject Yersinia outer proteins (Yops) into the host cytosol to subvert essential components of …

Yersinia are Gram-negative zoonotic bacteria that use a type III secretion system (T3SS) to
inject Yersinia outer proteins into the host cytosol to subvert essential components of innate …

Inflammasome-associated innate immune receptors sense host-cell targeting by the type III
secretion system (T3SS) of pathogenic Yersinia. In this issue of Cell Host & Microbe, Chung …

Type III secretion systems (T3SS) translocate effector proteins into target cells in order to
disrupt or modulate host cell signaling pathways and establish replicative niches. However …

Inflammasome assembly activates caspase-1 and initiates the inflammatory cell death
program pyroptosis, which is protective against numerous pathogens. Consequently …

Pathogenic Yersinia, including Y. pestis, the agent of plague in humans, and Y.
pseudotuberculosis, the related enteric pathogen, deliver virulence effectors into host cells …

Abstract The Yersinia virulence factor YopJ potently inhibits immune signaling in
macrophages by blocking activation of the signaling kinases TAK1 and IKK. In response …

Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-
negative bacteria, and secreted T3SS effectors can block key aspects of host cell signaling …

Microbial pathogens have evolved complex mechanisms to interface with host cells in order
to evade host defenses and replicate. However, mammalian innate immune receptors detect …