Review on how dangerous atherosclerotic plaques form and the critical role for defective
phagocytic clearance (or “efferocytosis”) of apoptotic macrophages in these lesions …

Accumulating evidence supports the notion that defective phagocytic clearance of dying
cells, or defective “efferocytosis,” is causally linked to the progression of advanced …

Efficient clearance of apoptotic cells, termed efferocytosis, critically regulates normal
homeostasis whereas defective uptake of apoptotic cells results in chronic and non …

Cardiovascular diseases represent 1 of the main causes of death worldwide, and
atherosclerosis is 1 of the major contributors leading to ischemic heart disease …

The walking dead: macrophage inflammation and death in ather... : Current Opinion in
Lipidology The walking dead: macrophage inflammation and death in atherosclerosis : Current …

Macrophage apoptosis occurs throughout all stages of atherosclerosis, yet new findings in
vivo suggest that the consequences of this event may be very different in early versus late …

Apoptotic cell death is an important feature of atherosclerotic plaques, and it seems to exert
both beneficial and detrimental effects depending on the cell type and plaque stage …

Throughout the process of atherosclerosis, lesional macrophages, smooth muscle cells, and
possibly endothelial cells undergo programmed cell death, or apoptosis. Under normal …

Macrophage apoptosis is an important feature of atherosclerotic plaque development.
Research directed at understanding the functional consequences of macrophage death in …

Atherosclerosis is a dynamic and progressive inflammatory process in the intimal layer of
large and medium-sized arteries, and it is the major contributor to the atherosclerotic …