Circulating adiponectin concentrations are reduced in obese individuals, and this reduction
has been proposed to have a crucial role in the pathogenesis of atherosclerosis and …

Adiponectin is produced predominantly by adipocytes and plays an important role in
metabolic and cardiovascular homeostasis through its insulin-sensitizing actions and anti …

Adiponectin has been identified as one of the “adipocytokines” that are derived only from
adipose tissue, and are abundantly present in circulating blood. Adiponectin has protective …

The increasing prevalence of diabetes and its complications heralds an alarming situation
worldwide. Obesity-associated changes in circulating adiponectin concentrations have the …

Adiponectin is a novel polypeptide that is highly specific to adipose tissue. In contrast to
other adipocytokines, adiponectin levels are decreased in obesity and associated …

Adipocyte-derived adiponectin is an insulin-sensitizing and antiatherosclerotic hormone,
and replenishment of adiponectin in animal models ameliorated insulin resistance and …

Adiponectin is an important adipocytokine secreted chiefly by fat containing adipocytes, and
plays a crucial role in glucose and lipid metabolism, inflammation and oxidative stress …

Adipose tissue, which classically has been considered as an energy-storing organ, is now
viewed as a massive source of bioactive substances such as leptin, tumor necrosis factor …

Obesity is strongly associated with metabolic and cardiovascular disorders. Adiponectin is
an adipose-derived plasma protein that is downregulated in subjects with obesity-related …

Adiponectin is the most abundant adipose-specific protein. Its expression is reduced in
obesity, insulin resistance and type 2 diabetes, and plasma concentrations are inversely …