The etiology of ischemic stroke is multifactorial. Although receiving less emphasis, genetic
causes make a significant contribution to ischemic stroke genesis, especially in early-onset …

Stroke represents an enormous health problem worldwide. It describes a clinical syndrome
which can be caused by a number of different pathologies, rather than a single disease …

Epidemiologic evidence supports a genetic predisposition to stroke. Recent advances,
primarily using the genome-wide association study approach, are transforming what we …

Stroke genetics includes several topics of clinical interest, including (1) molecular genetic
variations affecting risk of monogenic stroke syndromes;(2) molecular genetic variations …

Stroke, a leading cause of long-term disability and death worldwide, has a heritable
component. Recent gene discovery efforts have expanded the number of known single …

Stroke is the second leading cause of death worldwide and a complex, heterogeneous
condition. In this review, we provide an overview of the current knowledge on monogenic …

Stroke, ischaemic stroke and subtypes of ischaemic stroke display substantial heritability.
When compared with related vascular conditions, the number of established risk loci …

Driven by innovative technologies, novel analytical methods, and collaborations
unimaginable not long ago, our understanding of the role of genetic variation in stroke has …

Background The molecular basis for the genetic risk of ischemic stroke is likely to be
multigenic and influenced by environmental factors. Several small case-control studies have …

Background Various genome-wide association studies (GWAS) have been done in
ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have …