[HTML][HTML] Targeting circular RNAs as a therapeutic approach: current strategies and challenges
Significant progress has been made in circular RNA (circRNA) research in recent years.
Increasing evidence suggests that circRNAs play important roles in many cellular processes …
Increasing evidence suggests that circRNAs play important roles in many cellular processes …
[HTML][HTML] Circular RNAs as therapeutic agents and targets
LM Holdt, A Kohlmaier, D Teupser - Frontiers in physiology, 2018 - frontiersin.org
It has recently been reported that thousands of covalently linked circular RNAs (circRNAs)
are expressed from human genomes. circRNAs emerge during RNA splicing. circRNAs are …
are expressed from human genomes. circRNAs emerge during RNA splicing. circRNAs are …
Circular RNA: An emerging frontier in RNA therapeutic targets, RNA therapeutics, and mRNA vaccines
Circular RNAs (circRNA) is a class of natural (biogenic) or synthetic closed RNA without 5′
or 3′ ends. Meanwhile, their unique covalently-closed structures of circRNA prevent RNA …
or 3′ ends. Meanwhile, their unique covalently-closed structures of circRNA prevent RNA …
The design and synthesis of circular RNAs
P Obi, YG Chen - Methods, 2021 - Elsevier
Circular RNAs (circRNAs) are a novel class of RNAs distinguished by their single-stranded,
covalently-closed topology. Although initially perceived as rare byproducts of aberrant …
covalently-closed topology. Although initially perceived as rare byproducts of aberrant …
[HTML][HTML] Circular RNA: an important player with multiple facets to regulate its parental gene expression
T Shao, Y Pan, X Xiong - Molecular Therapy-Nucleic Acids, 2021 - cell.com
Circular RNAs (circRNAs), a novel type of endogenous RNAs with covalently closed-loop
structures, have become a new research hotspot in the RNA world. Their diversity, stability …
structures, have become a new research hotspot in the RNA world. Their diversity, stability …
[HTML][HTML] Circular RNAs: expression, localization, and therapeutic potentials
Circular RNAs (circRNAs) are RNAs with a unique circular structure that is generated from
back-splicing processes. These circular molecules were discovered more than 40 years ago …
back-splicing processes. These circular molecules were discovered more than 40 years ago …
Circular RNA and its mechanisms in disease: from the bench to the clinic
B Han, J Chao, H Yao - Pharmacology & therapeutics, 2018 - Elsevier
The emerging recognition of the functional roles of circular RNAs (circRNAs) has given rise
to a new perspective regarding our understanding of cellular physiology and disease …
to a new perspective regarding our understanding of cellular physiology and disease …
[HTML][HTML] Advances in circular RNA and its applications
X Zhao, Y Zhong, X Wang, J Shen… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Circular RNA (circRNA) is a novel endogenous non-coding RNA (ncRNA) that, like
microRNA (miRNA), is a rapidly emerging RNA research topic. CircRNA, unlike traditional …
microRNA (miRNA), is a rapidly emerging RNA research topic. CircRNA, unlike traditional …
[HTML][HTML] Circular RNAs: emerging regulators of the major signaling pathways involved in cancer progression
Simple Summary Circular RNAs (circRNAs) are single-stranded RNA molecules that form a
covalently closed loop structure. They are characterized by distinct features and …
covalently closed loop structure. They are characterized by distinct features and …
[HTML][HTML] Recent research progress on circular RNAs: Biogenesis, properties, functions, and therapeutic potential
Circular RNAs (circRNAs), an emerging family member of RNAs, have gained importance in
research due to their new functional roles in cellular physiology and disease progression …
research due to their new functional roles in cellular physiology and disease progression …