Craniosynostosis results from premature fusion of the cranial suture (s), which contain
mesenchymal stem cells (MSCs) that are crucial for calvarial expansion in coordination with …

Craniosynostosis is a major congenital craniofacial disorder characterized by the premature
fusion of cranial suture (s). Patients with severe craniosynostosis often have impairments in …

Cranial sutures are major growth centers for the calvarial vault, and their premature fusion
leads to a pathologic condition called craniosynostosis. This study investigates whether …

Cranial sutures separate the skull bones and house stem cells for bone growth and repair. In
Saethre-Chotzen syndrome, mutations in TCF12 or TWIST1 ablate a specific suture, the …

Craniosynostosis is a condition of complex etiology that always involves the premature
fusion of one or multiple cranial sutures and includes various anomalies of the soft and hard …

Normal extension and skull expansion is a synchronized process that prevails along the
osteogenic intersections of the cranial sutures. Cranial sutures operate as bone growth sites …

Sutures separate the flat bones of the skull and enable coordinated growth of the brain and
overlying cranium. The coronal suture is most commonly fused in monogenic …

The meninges lie in the interface between the skull and brain, harboring lymphatic
vasculature and skull progenitor cells (SPCs). How the skull and brain communicate …

Strategies to optimize clinical genetic diagnostic pathways by combining both targeted and
next-generation sequencing are discussed. In addition to improved genetic counseling …

Craniosynostosis, a developmental disorder resulting from premature closure of the gaps
(sutures) between skull bones, can be caused by excessive intramembranous ossification, a …