Abstract Background and Aims The PREDICT study recently showed that acutely
decompensated (AD) patients with cirrhosis can present three different clinical phenotypes …

Background & Aims Acute decompensation (AD) of cirrhosis is defined as the acute
development of ascites, gastrointestinal hemorrhage, hepatic encephalopathy, infection or …

Abstract Background and Aims Patients with decompensated cirrhosis are at increased risk
of mortality, even in absence of ACLF. The CLIF-C AD score (CLIF-C ADs) was proposed as …

Background and Aims: Patients with acute decompensated (AD) cirrhosis are frequently
readmitted to the hospital. An accurate predictive model for identifying high-risk patients may …

Background & Aims The prognostic impact of acute decompensation (AD), ie the
development of complications that require hospitalization, has recently been assessed …

Introduction Recently, based on data from the PREDICT study, the European Foundation for
the Study of Chronic Liver Failure (EF‐CLIF) consortium proposed pathophysiological …

Liver cirrhosis is traditionally classified into an asymptomatic phase, namely “compensated”
cirrhosis, and a symptomatic phase, namely “decompensated” cirrhosis, characterized by …

Introduction Acute-on-chronic liver failure (ACLF) is a dynamic syndrome that should be
assessed repeatedly. An algorithm for risk stratification in decompensated cirrhosis was …

Figure 1. The proposed disease course of liver cirrhosis. Early-stage cirrhosis begins with no
decompensation (ND) and is managed in an outpatient setting. Progression of the disease …

Background & Aims Acute decompensation (AD) of cirrhosis may present without acute-on-
chronic liver failure (ACLF)(AD-No ACLF), or with ACLF (AD-ACLF), defined by organ failure …