Direct oral anticoagulants in obesity: an updated literature review
J Sebaaly, D Kelley - Annals of Pharmacotherapy, 2020 - journals.sagepub.com
Objective: To review literature on the use of direct-acting oral anticoagulants (DOACs) in
patients with high body weight (BW) and/or high body mass index (BMI) and to make …
patients with high body weight (BW) and/or high body mass index (BMI) and to make …
Use of direct oral anticoagulants in morbidly obese patients
K Kido, JC Lee, T Hellwig… - … : The Journal of Human …, 2020 - Wiley Online Library
In 2016, the International Society on Thrombosis and Haemostasis (ISTH) published
guidelines advising caution when using direct oral anticoagulants (DOACs) in patients with …
guidelines advising caution when using direct oral anticoagulants (DOACs) in patients with …
[HTML][HTML] Use of the direct oral anticoagulants in obese patients: guidance from the SSC of the ISTH
K Martin, J Beyer‐Westendorf, BL Davidson… - Journal of Thrombosis …, 2016 - Elsevier
Four direct‐acting oral anticoagulants (DOACs)–the thrombin inhibitor dabigatran, and the
activated factor X (FXa) inhibitors apixaban, edoxaban, and rivaroxaban–are approved in …
activated factor X (FXa) inhibitors apixaban, edoxaban, and rivaroxaban–are approved in …
[HTML][HTML] Efficacy and safety of direct-acting oral anticoagulants (DOACs) in the overweight and obese
Obesity plays an essential role in the safety of pharmacologic drugs. There is paucity of data
for direct oral anticoagulants (DOACs) in the obese, despite these agents becoming more …
for direct oral anticoagulants (DOACs) in the obese, despite these agents becoming more …
A single center retrospective cohort study evaluating use of direct oral anticoagulants (DOACs) in morbidly obese veteran population
T Patil, M Lebrecht - Thrombosis Research, 2020 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) are preferred over warfarin for the
treatment of venous thromboembolism (VTE) as well as atrial fibrillation (AF). The efficacy …
treatment of venous thromboembolism (VTE) as well as atrial fibrillation (AF). The efficacy …
Direct oral anticoagulants in obese patients with venous thromboembolism: results of an expert consensus panel
RP Rosovsky, E Kline-Rogers, L Lake… - The American Journal of …, 2023 - Elsevier
In clinical practice, direct oral anticoagulants (DOACs) are increasingly used for venous
thromboembolism treatment and prevention. A substantial proportion of patients with venous …
thromboembolism treatment and prevention. A substantial proportion of patients with venous …
[HTML][HTML] Use of direct oral anticoagulants in patients with obesity for treatment and prevention of venous thromboembolism: updated communication from the ISTH …
KA Martin, J Beyer‐Westendorf, BL Davidson… - Journal of Thrombosis …, 2021 - Elsevier
Although direct‐acting oral anticoagulants (DOACs) have widespread first‐line use for
treatment and prevention of venous thromboembolism (VTE), uncertainty remains regarding …
treatment and prevention of venous thromboembolism (VTE), uncertainty remains regarding …
Evaluation of safety and efficacy outcomes of direct oral anticoagulants versus warfarin in normal and extreme body weights for the treatment of atrial fibrillation or …
AR Novak, C Shakowski, TC Trujillo, GC Wright… - Journal of Thrombosis …, 2022 - Springer
Despite evolving evidence, the use of direct oral anticoagulants (DOACs) in patients with
extremes of body weight remains controversial. This study aimed to measure the impact of …
extremes of body weight remains controversial. This study aimed to measure the impact of …
Pharmacokinetics and dosing regimens of direct oral anticoagulants in morbidly obese patients: an updated literature review
Y Zhao, M Guo, D Li, W Xu, C Pan… - Clinical and Applied …, 2023 - journals.sagepub.com
Data on the impact of morbid obesity (body mass index [BMI]≥ 40 kg/m2) on the
pharmacokinetics (PK), pharmacodynamics (PD) of direct oral anticoagulants (DOACs) are …
pharmacokinetics (PK), pharmacodynamics (PD) of direct oral anticoagulants (DOACs) are …
Evaluation of the efficacy of direct oral anticoagulants (DOACs) in comparison to warfarin in morbidly obese patients
C Kalani, E Awudi, T Alexander, G Udeani… - Hospital …, 2019 - Taylor & Francis
Purpose: There is limited clinical data evaluating anticoagulation with the direct oral
anticoagulants (DOACs) in morbidly obese patients. We sought to examine the efficacy in …
anticoagulants (DOACs) in morbidly obese patients. We sought to examine the efficacy in …