Tropane alkaloids: chemistry, pharmacology, biosynthesis and production

KL Kohnen-Johannsen, O Kayser - Molecules, 2019 - mdpi.com
Tropane alkaloids (TA) are valuable secondary plant metabolites which are mostly found in
high concentrations in the Solanaceae and Erythroxylaceae families. The TAs, which are …

Tropane alkaloid biosynthesis: a centennial review

JP Huang, YJ Wang, T Tian, L Wang, Y Yan… - Natural Product …, 2021 - pubs.rsc.org
Covering: 1917 to 2020 Tropane alkaloids (TAs) are a remarkable class of plant secondary
metabolites, which are characterized by an 8-azabicyclo [3.2. 1] octane (nortropane) ring …

Tropane and granatane alkaloid biosynthesis: a systematic analysis

N Kim, O Estrada, B Chavez, C Stewart Jr, JC D'Auria - Molecules, 2016 - mdpi.com
The tropane and granatane alkaloids belong to the larger pyrroline and piperidine classes of
plant alkaloids, respectively. Their core structures share common moieties and their …

[PDF][PDF] -Tropane alkaloids as medicinally useful natural products and their synthetic derivatives as new drugs.

G Grynkiewicz, M Gadzikowska - Pharmacological Reports, 2008 - if-pan.krakow.pl
Secondary metabolites of Solanaceae plants, sharing tropane skeleton as a common
structural feature, are sharply divided into two classes: tropine and ecgonine derivatives …

Tropane alkaloids (hyoscyamine, scopolamine and atropine) from genus Datura: Extractions, contents, syntheses and effects

Z Shi, W Zou, Z Zhu, Z Xiong, S Li, P Dong… - Industrial Crops and …, 2022 - Elsevier
Belonging to family Solanaceae, genus Datura is widely distributed all over the world and
famous for its narcosis and acesodyne in ancient China. And Datura is also annoying due to …

Chemotaxonomy and geographical distribution of tropane alkaloids

WJ Griffin, GD Lin - Phytochemistry, 2000 - Elsevier
This review illustrates the distribution of tropane alkaloids within the families Solanaceae,
Erythroxylaceae, Proteaceae, Euphorbiaceae, Rhizophoraceae, Convolvulaceae and …

Tropane alkaloid biosynthesis. A century old problem unresolved

AJ Humphrey, D O'hagan - Natural Product Reports, 2001 - pubs.rsc.org
Tropane alkaloid biosynthesis. A century old problem unresolved - Natural Product Reports (RSC
Publishing) DOI:10.1039/B001713M Royal Society of Chemistry View PDF VersionPrevious …

The tropane alkaloids

M Lounasmaa - The alkaloids: chemistry and pharmacology, 1988 - Elsevier
Publisher Summary This chapter describes the occurrence, syntheses, reactions,
biosynthesis, spectroscopy, pharmacology, and perspectives. The tropane alkaloids are a …

A Root-Expressed l-Phenylalanine:4-Hydroxyphenylpyruvate Aminotransferase Is Required for Tropane Alkaloid Biosynthesis in Atropa belladonna

MA Bedewitz, E Góngora-Castillo, JB Uebler… - The Plant …, 2014 - academic.oup.com
The tropane alkaloids, hyoscyamine and scopolamine, are medicinal compounds that are
the active components of several therapeutics. Hyoscyamine and scopolamine are …

Plant tropane alkaloid biosynthesis evolved independently in the Solanaceae and Erythroxylaceae

J Jirschitzka, GW Schmidt, M Reichelt… - Proceedings of the …, 2012 - National Acad Sciences
The pharmacologically important tropane alkaloids have a scattered distribution among
angiosperm families, like many other groups of secondary metabolites. To determine …