The effects of phytic acid and phytic acid/zinc mixtures on renal urolith development in an
animal model of nephrolitiasis were studied. Male rats were divided into four groups of 15 …

The phytate urinary levels in a group of active calcium oxalate stone formers were studied
and compared with those found in healthy people. Urinary phytate was significantly lower for …

On the basis of what we know about urinary supersaturation and particle growth inhibitors
stone formation is unlikely to start from free crystalluric particles in the renal tubule …

An experimental model that enables the close simulation of conditions prevailing in the
kidney during the formation of stones, using living tissue of pig urinary bladder, was …

PURPOSE: We measured and compared 3 activities of inositol hexaphosphate, also known
as phytate, to explore their importance in relation to antilithogenic potential. MATERIALS …

1. Bladder stones composed of calcium hydrogen phosphate dihydrate, calcium oxalate
mono-and di-hydrate and magnesium ammonium phosphate hexahydrate (struvite) were …

To better understand the pathogenesis of nephrolithiasis, we developed a new animal
model that closely mimics human calcium oxalate stone disease. Rats were treated with a …

Most renal stones in humans are composed of calcium oxalate. An increase in urinary
oxalate levels has been shown to result in renal epithelial cell injury and crystal retention …

Magnesium oxide, magnesium hydroxide, magnesium sulfate, magnesium trisilicate, and
magnesium citrate were added to a calcium-oxalate lithogenic diet in order to determine …

Purpose: The availability of various transgenic and knockout mice provides an excellent
opportunity to better understand the pathophysiology of calcium oxalate stone disease …