Role of daratumumab in the frontline management of multiple myeloma: a narrative review

S Yadav, S Gundeti, A Bhave, U Deb… - Expert Review of …, 2023 - Taylor & Francis
Introduction The prevalence of multiple myeloma (MM) has gradually increased over the last
few decades in India due to growing population, better disease awareness, and improved …

Daratumumab for the management of newly diagnosed and relapsed/refractory multiple myeloma: current and emerging treatments

M Offidani, L Corvatta, S Morè, D Nappi… - Frontiers in …, 2021 - frontiersin.org
Immunotherapy is changing the paradigm of multiple myeloma (MM) management and
daratumumab is the first-in-class human monoclonal antibody targeting CD38 approved for …

Daratumumab in untreated newly diagnosed multiple myeloma

N Abdallah, SK Kumar - Therapeutic advances in …, 2019 - journals.sagepub.com
The treatment of multiple myeloma has evolved markedly in the last decade, but mortality
remains high, emphasizing the need for more effective therapies. Daratumumab, a fully …

Daratumumab as single agent in relapsed/refractory myeloma patients: a retrospective real-life survey

U Markovic, A Romano, V Del Fabro… - Frontiers in …, 2021 - frontiersin.org
Background The anti-CD38 monoclonal antibody daratumumab is approved as a single
agent for the treatment of patients with relapsed/refractory multiple myeloma (RRMM) who …

Daratumumab: a review in combination therapy for transplant-eligible newly diagnosed multiple myeloma

YN Lamb - Drugs, 2020 - Springer
Intravenous daratumumab (DARZALEX®), a human monoclonal antibody targeting CD38, is
approved in the EU and USA for use in combination with bortezomib, thalidomide and …

Daratumumab for the treatment of multiple myeloma: A review of clinical applicability and operational considerations

JR Arnall, KT Maples, RD Harvey… - Annals of …, 2022 - journals.sagepub.com
Objective: To review the available data for the efficacy and safety of daratumumab in the
treatment of multiple myeloma (MM), both in the newly diagnosed and relapsed/refractory …

Efficacy and safety of daratumumab in the treatment of multiple myeloma: a systematic review and meta-analysis

Y Wang, Y Li, Y Chai - Journal of International Medical …, 2021 - journals.sagepub.com
Objective To systematically evaluate the efficacy and safety of combination regimens
containing daratumumab in patients with multiple myeloma (MM). Methods A systematic …

[HTML][HTML] Efficacy and safety of daratumumab in the treatment of relapsed/refractory multiple myeloma: A meta-analysis of randomized controlled trials

ZY Huang, XQ Jin, QL Liang, DY Zhang, H Han… - Medicine, 2023 - journals.lww.com
Background: Daratumumab as a monoclonal antibody has shown promising results in the
treatment of relapsed/refractory multiple myeloma (RRMM). However, the efficacy and safety …

[HTML][HTML] Meta-analysis of the efficacy and safety of daratumumab in the treatment of multiple myeloma

P Wang, SY Jin - World Journal of Clinical Cases, 2023 - ncbi.nlm.nih.gov
BACKGROUND The treatment of multiple myeloma has significantly progressed over the
past half-century. The purpose of this study was to perform a systematic review and meta …

New developments in the treatment of multiple myeloma–clinical utility of daratumumab

C McEllistrim, J Krawczyk… - Biologics: Targets and …, 2017 - Taylor & Francis
Multiple myeloma is a clonal disorder of plasma cells that is currently considered incurable.
CD38 is a 46 kDa type II transmembrane glycoprotein that is highly expressed on myeloma …