Expedition of sulfur‐containing heterocyclic derivatives as cytotoxic agents in medicinal chemistry: A decade update
K Laxmikeshav, P Kumari… - Medicinal Research …, 2022 - Wiley Online Library
This review article proposes a comprehensive report of the design strategies engaged in the
development of various sulfur‐bearing cytotoxic agents. The outcomes of various studies …
development of various sulfur‐bearing cytotoxic agents. The outcomes of various studies …
Synthetic and anti-cancer activity aspects of 1, 3, 4-thiadiazole containing bioactive molecules: A concise review
Despite significant advances in understanding cancer pathogenesis, it continues to be one
of the leading causes of death. Thus, there is an urgent need for the development of novel …
of the leading causes of death. Thus, there is an urgent need for the development of novel …
[HTML][HTML] A review: Medicinally important nitrogen sulphur containing heterocycles
Nitrogen sulphur containing heterocycles have specific properties due to which they can be
used as a potential material in a different type of industries such as medicinal …
used as a potential material in a different type of industries such as medicinal …
Sulfur containing scaffolds in drugs: synthesis and application in medicinal chemistry
The impact of the development of sulfur therapeutics is instrumental to the evolution of the
pharmaceutical industry. Sulfur-derived functional groups can be found in a broad range of …
pharmaceutical industry. Sulfur-derived functional groups can be found in a broad range of …
The importance of sulfur-containing motifs in drug design and discovery
Introduction Sulfur-containing functional groups are privileged motifs that occur in various
pharmacologically effective substances and several natural products. Various functionalities …
pharmacologically effective substances and several natural products. Various functionalities …
Disulfide and multisulfide antitumor agents and their modes of action
SH Lee - Archives of pharmacal research, 2009 - Springer
A variety of natural products that contain disulfide or multisulfide bonds were found to
display potent biological activities, including antitumor activities. At the center of these …
display potent biological activities, including antitumor activities. At the center of these …
Role of sulphur-heterocycles in medicinal chemistry: An update
From many decades, S-heterocycles have maintained their status as an important part and
core of FDA approved drugs and medicinally active compounds. With exhaustive exploration …
core of FDA approved drugs and medicinally active compounds. With exhaustive exploration …
Thiazole in the targeted anticancer drug discovery
Cancer is known as one of the main causes of death in the world; and many compounds
have been synthesized to date with potential use in cancer therapy. Thiazole is a versatile …
have been synthesized to date with potential use in cancer therapy. Thiazole is a versatile …
Thiophene-based derivatives as anticancer agents: An overview on decade's work
S Pathania, PA Chawla - Bioorganic Chemistry, 2020 - Elsevier
Heterocyclic compounds hold a pivotal place in medicinal chemistry due to their wide range
of biological activities and thus, are exhaustively explored in the field of drug design and …
of biological activities and thus, are exhaustively explored in the field of drug design and …
[HTML][HTML] Thiadiazines, N,N-Heterocycles of Biological Relevance
The 3, 5-disubstituted tetrahydro-2 H-1, 3, 5-thiadiazine-2-thione scaffold has found many
applications in recent years. This review is aimed at highlighting the most important aspects …
applications in recent years. This review is aimed at highlighting the most important aspects …
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