[HTML][HTML] The influence of sleep on fear extinction in trauma-related disorders

EF Pace-Schott, J Seo, R Bottary - Neurobiology of stress, 2023 - Elsevier
Abstract In Posttraumatic Stress Disorder (PTSD), fear and anxiety become dysregulated
following psychologically traumatic events. Regulation of fear and anxiety involves both high …

Sleep and REM sleep disturbance in the pathophysiology of PTSD: the role of extinction memory

EF Pace-Schott, A Germain, MR Milad - Biology of mood & anxiety …, 2015 - Springer
Post-traumatic stress disorder (PTSD) is accompanied by disturbed sleep and an impaired
ability to learn and remember extinction of conditioned fear. Following a traumatic event, the …

Associations of sleep measures with neural activations accompanying fear conditioning and extinction learning and memory in trauma-exposed individuals

J Seo, KI Oliver, C Daffre, KN Moore, S Gazecki… - Sleep, 2022 - academic.oup.com
Abstract Study Objectives Sleep disturbances increase risk of posttraumatic stress disorder
(PTSD). Sleep effects on extinction may contribute to such risk. Neural activations to fear …

Sleep disruption, safety learning, and fear extinction in humans: implications for posttraumatic stress disorder

LD Straus, SPA Drummond, VB Risbrough… - … neurobiology of PTSD, 2018 - Springer
Fear learning is critical in the development and maintenance of posttraumatic stress disorder
(PTSD) symptoms, and safety learning and extinction are necessary for recovery. Studies in …

Sleep-specific mechanisms underlying posttraumatic stress disorder: integrative review and neurobiological hypotheses

A Germain, DJ Buysse, E Nofzinger - Sleep medicine reviews, 2008 - Elsevier
Posttraumatic stress disorder (PTSD) is a prevalent disorder that is associated with poor
clinical and health outcomes, and considerable health care utilization and costs. Recent …

A review of the relationship between emotional learning and memory, sleep, and PTSD

PJ Colvonen, LD Straus, D Acheson… - Current Psychiatry …, 2019 - Springer
Abstract Purpose of Review The emotional memory and learning model of PTSD posits
maladaptive fear conditioning, extinction learning, extinction recall, and safety learning as …

REM sleep and safety signal learning in posttraumatic stress disorder: a preliminary study in military veterans

LD Straus, SB Norman, VB Risbrough, DT Acheson… - Neurobiology of …, 2018 - Elsevier
Abstract Background Posttraumatic Stress Disorder (PTSD) is associated with a number of
negative physical and mental health consequences. Fear conditioning plays an important …

Sleep alterations following exposure to stress predict fear-associated memory impairments in a rodent model of PTSD

WM Vanderheyden, SA George, L Urpa… - Experimental brain …, 2015 - Springer
Sleep abnormalities, such as insomnia, nightmares, hyper-arousal, and difficulty initiating or
maintaining sleep, are diagnostic criteria of posttraumatic stress disorder (PTSD). The vivid …

Fear conditioning, safety learning, and sleep in humans

AJ Marshall, DT Acheson, VB Risbrough… - Journal of …, 2014 - Soc Neuroscience
Fear conditioning is considered an animal model of post-traumatic stress disorder. Such
models have shown fear conditioning disrupts subsequent rapid eye movement sleep …

Sleep deprivation facilitates extinction of implicit fear generalization and physiological response to fear

K Kuriyama, T Soshi, Y Kim - Biological psychiatry, 2010 - Elsevier
BACKGROUND:: Neuroendocrine hormones, which regulate both homeostasis and stress
responses, provide homeostatic recovery and sleep suppression to brains under stress. We …