[HTML][HTML] Candida Biofilms: Threats, Challenges, and Promising Strategies

M Cavalheiro, MC Teixeira - Frontiers in medicine, 2018 - frontiersin.org
Candida species are fungal pathogens known for their ability to cause superficial and
systemic infections in the human host. These pathogens are able to persist inside the host …

Candida Biofilms: An Update on Developmental Mechanisms and Therapeutic Challenges

PP de Barros, RD Rossoni, CM de Souza, L Scorzoni… - Mycopathologia, 2020 - Springer
Fungi of the genus Candida are important etiological agents of superficial and life-
threatening infections in individuals with a compromised immune system. One of the main …

Future directions for anti-biofilm therapeutics targeting Candida

JE Nett - Expert review of anti-infective therapy, 2014 - Taylor & Francis
While proliferating in its most common mode of growth, a biofilm, Candida spp. exhibit
increased resistance to available antifungal agents. These adherent communities are …

Our current clinical understanding of Candida biofilms: where are we two decades on?

G Ramage, E Borghi, CF Rodrigues, R Kean… - APMIS, 2023 - Wiley Online Library
Clinically we have been aware of the concept of Candida biofilms for many decades, though
perhaps without the formal designation. Just over 20 years ago the subject emerged on the …

[HTML][HTML] Antifungal drug-resistance mechanisms in Candida biofilms

J Kaur, CJ Nobile - Current opinion in microbiology, 2023 - Elsevier
Highlights•Few classes of antifungal drugs currently exist to treat fungal infections.•Infections
caused by Candida biofilms can be resistant to known antifungal drugs.•Growth in the …

Candida Biofilms and the Host: Models and New Concepts for Eradication

H Tournu, P Van Dijck - International journal of microbiology, 2012 - Wiley Online Library
Biofilms define mono‐or multispecies communities embedded in a self‐produced protective
matrix, which is strongly attached to surfaces. They often are considered a general threat not …

Biofilm lifestyle of Candida: a mini review

CJ Seneviratne, L Jin, LP Samaranayake - Oral diseases, 2008 - Wiley Online Library
Candida is the major fungal pathogen of humans causing a variety of afflictions ranging from
superficial mucosal diseases to deep seated mycoses. Biofilm formation is a major virulence …

Candida biofilm resistance

PK Mukherjee, J Chandra - Drug resistance updates, 2004 - Elsevier
Device-related infections in most nosocomial diseases can be traced to the formation of
biofilms (microbial communities encased within polysaccharide-rich extracellular matrix) by …

Biofilms and their role in the resistance of pathogenic Candida to antifungal agents

C d'Enfert - Current drug targets, 2006 - ingentaconnect.com
Fungal pathogens of the genus Candida form biofilms on catheters and prosthetic devices.
These threedimensional structures composed of yeast and hyphal cells embedded in an …

[HTML][HTML] Antifungal therapy of Candida biofilms: Past, present and future

OH Ajetunmobi, H Badali, JA Romo, G Ramage… - Biofilm, 2023 - Elsevier
Virtually all Candida species linked to clinical candidiasis are capable of forming highly
resistant biofilms on different types of surfaces, which poses an additional significant threat …