Altered levels of cytokines and acute-phase proteins have been described in the blood and
brain of patients with Alzheimer's disease. Microglia are resident cells of the brain and …

Inflammation plays an important role in progressive degenerative diseases of the CNS, such
as Alzheimer's disease, which represents the major cause of cognitive impairment in old …

Alzheimer's disease (AD) is a progressive degenerative disease of the brain and the most
frequent cause of dementia among elderly. The etiology of AD is still obscure, but genetic …

Alzheimer's disease is an important public concern with rising prevalence across the globe.
While many therapeutic approaches for Alzheimer's disease have been developed, there …

Background The role of the innate immune system in Alzheimer's disease (AD) and
neurodegenerative disease susceptibility has recently been highlighted in genetic studies …

Background: Neuropathological studies supported by experimental animal studies show that
the constituents of the innate immunity are intimately involved in the early steps of the …

Inflammation is associated with the degeneration of brain areas in Alzheimer's disease (AD).
Pro-inflammatory cytokines and other immune-regulatory molecules are overexpressed in …

One of the major obstacles confronting the formulation of a mechanistic understanding for
Alzheimer's disease (AD) is its immense complexity—a complexity that traverses the full …

Alzheimer's disease (AD) is a neurodegenerative disorder, most cases of which lack a clear
causative event. This has made the disease difficult to characterize and, thus, diagnose …

The role of the brain's innate immune system in Alzheimer pathogenesis is now well
established. Proinflammatory cytokines elaborated by this system, in particular activated …