Prevalence of diabetes continues to increase world-wide and now involves about half a
billion people globally. 1–3 The majority of this increase involves patients diagnosed with …

The growing incidence of type 2 diabetes (T2D) is a significant health concern, representing
90% of diabetes cases worldwide. As the disease progresses, resultant insulin deficiency …

Since the first successful use of insulin in 1921 to treat diabetes at Toronto General Hospital,
the major advances in development of the medication itself have taken place in parallel with …

Diabetes mellitus affects approximately 18 million people in the United States, which is
approximately 6% of the overall population, and over 800,000 new cases are diagnosed …

The United States faces a shortage of both primary care physicians (PCPs) and
endocrinologists—the two groups of clinicians who provide the majority of care to people …

Before the discovery of insulin and diet restriction, the Joslin Clinic reported very high
mortality rates for type 1 diabetes (T1D) that ranged from 824 per 1000 individuals aged 10 …

Technological advances have had a major effect on the management of type 1 diabetes. In
addition to blood glucose meters, devices used by people with type 1 diabetes include …

Type 1 diabetes mellitus is a disorder of glucose regulation characterized by autoimmune
destruction of the insulin-producing pancreatic β-cells and the need for lifelong insulin …

ABSTRACT Type 1 diabetes (T1D) is an autoimmune disease characterized by progressive
pancreatic beta-cell loss resulting in insulin deficiency and hyperglycemia. Exogenous …

Type 2 diabetes is a progressive disease characterized by relentless deterioration of
pancreaticcell function. 1 With the increasing incidence of type 2 diabetes, especially among …