Background. The isolation of tigecycline‐resistant Acinetobacter baumannii in recent years
has brought great difficulties to clinical prevention and treatment. Purpose. To explore the …

Background and aims Infection and outbreaks caused by tigecycline-resistant Acinetobacter
baumannii strains have reported worldwide. However, the relative contribution of the efflux …

Objective Acinetobacter baumannii has emerged as a problematic hospital pathogen and
tigecycline is among the few remaining antibiotics retaining activity against multidrug …

Acinetobacter baumannii is an important human pathogen responsible for a various type of
infections. These bacterial strains are generally resistant to numerous antibiotics. Therefore …

Aim: To analyze the expression and regulation of resistance-nodulation-division (RND)
efflux systems in clinical tigecycline-nonsusceptible (TNS) Acinetobacter baumannii …

The emergence of tigecycline resistance has increased in the last years. Although
tigecycline-resistant Acinetobacter baumannii isolates were described all over the world, few …

Because of its remarkable ability to acquire antibiotic resistance and to survive in
nosocomial environments, Acinetobacter baumannii has become a significant nosocomial …

Objectives To investigate the mechanisms of tigecycline resistance in isogenic
Acinetobacter baumannii isolate pairs as well as 65 unique clinical A. baumannii isolates …

Tigecycline is regarded as a last-resort treatment for multidrug-resistant Acinetobacter
baumannii. However, tigecycline resistance in A. baumannii has increased worldwide. In …

The mechanism of tigecycline resistance in A. baumannii remains largely unclear. In this
study, we selected a tigecycline-resistant and a tigecycline-susceptible strain from a …