[HTML][HTML] Natural products targeting the mitochondria in cancers

Y Yang, PY He, Y Zhang, N Li - Molecules, 2020 - mdpi.com
There are abundant sources of anticancer drugs in nature that have a broad prospect in
anticancer drug discovery. Natural compounds, with biological activities extracted from …

[HTML][HTML] Natural products and mitochondrial allies in colorectal cancer therapy

F Wei, Q Nian, M Zhao, Y Wen, Y Yang, J Wang… - Biomedicine & …, 2023 - Elsevier
Colorectal cancer (CRC) is a globally prevalent malignancy with a high potential for
metastasis. Existing cancer treatments have limitations, including drug resistance and …

[HTML][HTML] Natural agents targeting mitochondria in cancer

S Mani, G Swargiary, KK Singh - International journal of molecular …, 2020 - mdpi.com
Mitochondria are the key energy provider to highly proliferating cancer cells, and are
subsequently considered one of the critical targets in cancer therapeutics. Several …

The role of herbal bioactive components in mitochondria function and cancer therapy

F Tao, Y Zhang, Z Zhang - Evidence‐Based Complementary …, 2019 - Wiley Online Library
Mitochondria are highly dynamic double‐membrane organelles which play a well‐
recognized role in ATP production, calcium homeostasis, oxidation‐reduction (redox) status …

[HTML][HTML] Mitochondria targeting nano agents in cancer therapeutics (Review) Retraction in/10.3892/ol. 2020.12101

XY Zhang, PY Zhang - Oncology letters, 2016 - spandidos-publications.com
Mitochondria have emerged as noteworthy therapeutic targets as their physiological
functions are often altered in pathological conditions such as cancer. The electronic …

Novel mitochondria-targeted drugs for cancer therapy

JL Fialova, M Raudenska, M Jakubek… - Mini Reviews in …, 2021 - ingentaconnect.com
The search for mitochondria-targeted drugs has dramatically risen over the last decade.
Mitochondria are essential organelles serving not only as a powerhouse of the cell but also …

[HTML][HTML] The multifaceted roles of natural products in mitochondrial dysfunction

Q Chen, D Ruan, J Shi, D Du, C Bian - Frontiers in Pharmacology, 2023 - frontiersin.org
Mitochondria are the primary source of energy production in cells, supporting the metabolic
demand of tissue. The dysfunctional mitochondria are implicated in various diseases …

Polyphenols as mitochondria-targeted anticancer drugs

S Gorlach, J Fichna, U Lewandowska - Cancer Letters, 2015 - Elsevier
Mitochondria are the respiratory and energetic centers of the cell where multiple intra-and
extracellular signal transduction pathways converge leading to dysfunction of those …

The role of mitochondria in phytochemically mediated disease amelioration

YC Koh, CT Ho, MH Pan - Journal of agricultural and food …, 2023 - ACS Publications
Mitochondrial dysfunction may cause cell death, which has recently emerged as a cancer
prevention and treatment strategy mediated by chemotherapy drugs or phytochemicals …

[HTML][HTML] Mitochondria deregulations in cancer offer several potential targets of therapeutic interventions

C Musicco, A Signorile, V Pesce… - International Journal of …, 2023 - mdpi.com
Mitochondria play a key role in cancer and their involvement is not limited to the production
of ATP only. Mitochondria also produce reactive oxygen species and building blocks to …