In humans, mutations in the L1 cell adhesion molecule are associated with a neurological
syndrome termed CRASH, which includes corpus callosum agenesis, mental retardation …

The neural adhesion molecule L1, a member of the immunoglobulin superfamily of cell
recognition molecules, performs important functions in the developing and adult nervous …

The neural cell adhesion molecule L1 mediates the axon outgrowth, adhesion, and
fasciculation necessary for proper development of synaptic connections. Mutations of human …

Mutations in the cell adhesion molecule L1 cause severe developmental anomalies in the
human nervous system. Recent descriptions of L1 gene knock-out mice from three research …

L1 is a neural cell adhesion molecule mainly involved in axon guidance and neuronal
migration during brain development. Mutations in the human L1 gene give rise to a complex …

Cell recognition molecules are involved in nervous system development and participate in
synaptic plasticity in the adult brain. The close homolog of L1 (CHL1), a recently identified …

The L1 adhesion molecule regulates axon growth and is mutated in the X-linked mental
retardation syndrome CRASH (acronym for corpus callosum agenesis, retardation, aphasia …

L1, a neural cell adhesion molecule of the immunoglobulin superfamily, is involved in
neuronal migration and differentiation and axon outgrowth and guidance. Mutations in the …

The neuronal cell adhesion molecule L1 (L1CAM) is a transmembrane glycoprotein
belonging to the immunoglobulin superfamily and is essential in the development of the …

A new mouse line has been produced in which the sixth Ig domain of the L1 cell adhesion
molecule has been deleted. Despite the rather large deletion, L1 expression is preserved at …