Analgesics, particularly opioids, have been routinely used in the emergency treatment of
ischemic chest pain for a long time. In the past two decades; however, several studies have …

Acute myocardial infarction—already one of the most common causes of chest pain in the
United States and in other developed countries—is quickly becoming one of the most …

Background An adverse interaction whereby opioids impair and delay the gastrointestinal
absorption of oral P2Y12 inhibitors has been established, however the clinical significance …

BACKGROUND: Many patients who suffer from acute chest pain are transported by
ambulance. It is not known how often treatment prior to hospital admission is optimal and …

Chest pain is the prevalent symptom at presentation in patients with acute myocardial
infarction (AMI). Despite the complete absence of rigorous studies designed to assess the …

Opioid analgesics are largely implemented for the relief of acute pain in several clinical
settings, including among patients with acute coronary syndrome (ACS) undergoing …

Background We sought to determine if an association exists between prehospital chest pain
severity and markers of myocardial injury. Methods and Results Patients with confirmed ST …

In the treatment of acute coronary syndromes, reduction of sympathetic stress and
catecholamine release is an important therapeutic goal. One method used to achieve this …

Background Studies have shown disparate results on the consequences of morphine use in
ST-segment elevation myocardial infarction (STEMI). No study has evaluated alternative …

Objectives This study examined if sex differences in prehospital pain scores, opioid
administration, and clinical outcomes exist in acute coronary syndrome (ACS) patients …