Bile acids (BAs) are originally known as detergents essential for the digestion and
absorption of lipids. In recent years, extensive research has unveiled new functions of BAs …

Bile acids (BAs) can regulate their own metabolism and transport as well as other key
aspects of metabolic homeostasis via dedicated (nuclear and G protein-coupled) receptors …

Bile acids (BAs) are the major metabolic product of cholesterol, having detergent-like
activities and being responsible for absorption of lipid and lipid-soluble vitamins. In addition …

Bile acids (BAs) function as detergents promoting nutrient absorption and as hormones
regulating nutrient metabolism. Most BAs are key regulatory factors of physiological …

Bile acids (BAs) play a crucial role in nutrient absorption and act as key regulators of lipid
and glucose metabolism and immune homeostasis. Through the enterohepatic circulation …

Highlights•Cholestatic liver diseases and bile acid homeostasis are closely
connected.•Numerous signaling molecules are associated with bile acid transporters, tight …

Bile acids (BAs) are not only facilitators participating in the absorption of dietary lipids and
soluble vitamins, but are also important signaling molecules exerting versatile …

Bile acids (BAs) are cholesterol-derived metabolites that facilitate the intestinal absorption
and transport of dietary lipids. Recently, BAs also emerged as pivotal signaling molecules …

Chronic cholestatic liver diseases, such as primary biliary cholangitis (PBC) and primary
sclerosing cholangitis (PSC), are associated with bile stasis and gradually progress to …

Bile acids (BAs), a group of structurally diverse molecules that are primarily synthesized in
the liver from cholesterol, are the chief components of bile. Besides their well‐established …