By Michael addition polymerization of N, N'-cystaminebisacrylamide (CBA) with variable
ratios of 4-amino-1-butanol (ABOL) and ethylene diamine (EDA) or triethylenetetramine …

Purpose RNA interference (RNAi) is a process by which small interfering RNAs (siRNA)
induce sequence-specific gene silencing. Therefore, siRNA is an emerging promise as a …

We synthesized poly (amidoamine) s with pendant primary amines and flexible backbone
(polymers 1–3) by Michael polyaddition of N‐tert‐butyloxycarbonyl (N‐Boc) protected …

A group of novel poly (amido amine) homo-and copolymers (PAAs) containing secondary
and tertiary amine groups in their main chain and different structures in the bisacrylamide …

The development of safe and efficient gene delivery vectors is an essential prerequisite for
successful gene therapy. As viral vectors suffer from inherent disadvantages, cationic …

In the development of potent polymeric gene carriers for gene therapy, a good interaction
between the polymer and the nucleotide is indispensable to form small and stable …

To evaluate the effect of quaternary nicotinamide pendant groups on gene delivery
properties, a series of poly (amido amine)(co) polymers were synthesized by Michael …

A group of bioreducible poly (amido amine) s containing multiple disulfide linkages in main
chain and oligoamines in side chain (SS–PAOAs) were prepared by Michael-type …

Purpose Use of RNA interference as novel therapeutic strategy is hampered by inefficient
delivery of its mediator, siRNA, to target cells. Cationic polymers have been thoroughly …

A series of novel bioreducible poly (amido amine) s containing multiple disulfide linkages
(SS-PAAs) were synthesized and evaluated as nonviral gene vectors. These linear SS-PAAs …