Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease with distinct
phenotypes, each having distinct treatment needs. Eosinophilic airway inflammation is …

A number of recent post hoc analyses of clinical trials have demonstrated that higher blood
eosinophil counts predict greater inhaled corticosteroid (ICS) effects on exacerbation …

In an era of precision medicine, it seems regressive that we do not use stratified approaches
to direct treatment of oral corticosteroids during an exacerbation of chronic obstructive …

Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease. COPD
exacerbations have a major impact on morbidity and mortality. The etiology of COPD …

Chronic obstructive pulmonary disease (COPD) is a heterogeneous disorder and patients
respond differently to treatment. Blood eosinophils are a potential biomarker to stratify …

Background Chronic obstructive pulmonary disease (COPD) is characterised by progressive
airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which …

Treating patients hospitalised with acute exacerbations of chronic obstructive pulmonary
disease (COPD) usually involves administering systemic corticosteroids. The many …

Introduction There is an interest in the role of blood eosinophils for predicting inhaled
corticosteroid (ICS) response in chronic obstructive pulmonary disease (COPD). Most data …

Rationale: Exacerbations of chronic obstructive pulmonary disease (COPD) and responses
to treatment are heterogeneous. Objectives: Investigate the usefulness of blood eosinophils …

The heterogeneity of chronic obstructive pulmonary disease (COPD) creates many
diagnostic, prognostic, treatment and management challenges, as the pathogenesis of …