[HTML][HTML] The interplay between metabolic homeostasis and neurodegeneration: insights into the neurometabolic nature of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal, neurodegenerative disease that is
characterized by the selective degeneration of upper motor neurons and lower spinal motor …
characterized by the selective degeneration of upper motor neurons and lower spinal motor …
Energy metabolism in ALS: an underappreciated opportunity?
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive and fatal
neurodegenerative disorder that primarily affects motor neurons. Despite our increased …
neurodegenerative disorder that primarily affects motor neurons. Despite our increased …
AMPK signalling and defective energy metabolism in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is caused by selective loss of upper and lower motor
neurons by complex mechanisms that are incompletely understood. Motor neurons are …
neurons by complex mechanisms that are incompletely understood. Motor neurons are …
Metabolic dysregulation in amyotrophic lateral sclerosis: challenges and opportunities
A Joardar, E Manzo, DC Zarnescu - Current genetic medicine reports, 2017 - Springer
Abstract Purpose of Review Amyotrophic lateral sclerosis (ALS) is a progressive
neurodegenerative disease for which there is no cure and treatments are at best palliative …
neurodegenerative disease for which there is no cure and treatments are at best palliative …
[HTML][HTML] Metabolic dysfunctions in amyotrophic lateral sclerosis pathogenesis and potential metabolic treatments
TW Tefera, K Borges - Frontiers in neuroscience, 2017 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease primarily
characterized by loss of motor neurons in brain and spinal cord. The death of motor neurons …
characterized by loss of motor neurons in brain and spinal cord. The death of motor neurons …
[HTML][HTML] Altered bioenergetics and metabolic homeostasis in amyotrophic lateral sclerosis
AT Nelson, D Trotti - Neurotherapeutics, 2022 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that
primarily affects motor neurons and causes muscle atrophy, paralysis, and death. While a …
primarily affects motor neurons and causes muscle atrophy, paralysis, and death. While a …
Nutritional and metabolic factors in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease that is
classically thought to impact the motor system. Over the past 20 years, research has started …
classically thought to impact the motor system. Over the past 20 years, research has started …
Skeletal muscle metabolism: origin or prognostic factor for amyotrophic lateral sclerosis (ALS) development?
C Quessada, A Bouscary, F René, C Valle, A Ferri… - Cells, 2021 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
progressive and selective loss of motor neurons, amyotrophy and skeletal muscle paralysis …
progressive and selective loss of motor neurons, amyotrophy and skeletal muscle paralysis …
Roots to start research in amyotrophic lateral sclerosis: molecular pathways and novel therapeutics for future
D Harikrishnareddy, S Misra, S Upadhyay… - Reviews in the …, 2015 - degruyter.com
Amyotrophic lateral sclerosis (ALS) is a devastating neurological disease that rapidly
progresses from mild motor symptoms to severe motor paralysis and premature death. There …
progresses from mild motor symptoms to severe motor paralysis and premature death. There …
Neuromuscular junction destruction during amyotrophic lateral sclerosis: insights from transgenic models
L Dupuis, JP Loeffler - Current opinion in pharmacology, 2009 - Elsevier
Amyotrophic lateral sclerosis (ALS) represents the major adult-onset motor neuron disease.
Analyses of ALS animal models have shown that motor neuron death starts with …
Analyses of ALS animal models have shown that motor neuron death starts with …