Inhibition of scopolamine‐induced memory and mitochondrial impairment by betanin

A Salimi, M Sabur, M Dadkhah… - Journal of Biochemical …, 2022 - Wiley Online Library
Mitochondrial dysfunction and oxidative stress are identified to contribute to the mechanisms
responsible for the pathogenesis of Alzheimer's disease (AD). Scopolamine (SCO) as a …

Mitochondrial involvement in memory impairment induced by scopolamine in rats

M Wong-Guerra, J Jiménez-Martin… - Neurological …, 2017 - Taylor & Francis
Objective: Scopolamine (SCO) administration to rats induces molecular features of AD and
other dementias, including impaired cognition, increased oxidative stress, and imbalanced …

Organosulfur compound protects against memory decline induced by scopolamine through modulation of oxidative stress and Na+/K+ ATPase activity in mice

FD da Silva, MP Pinz, RL de Oliveira… - Metabolic Brain …, 2017 - Springer
The present study investigated the possible effect of BMMS in protecting against memory
impairment in an Alzheimer's disease model induced by scopolamine in mice. Another …

Methylene blue improves streptozotocin-induced memory deficit by restoring mitochondrial function in rats

L Li, L Qin, H Lu, PJ Li, YJ Song, RL Yang - Brain research, 2017 - Elsevier
The pathogenesis of Alzheimer's disease (AD) is well documented to involve mitochondrial
dysfunction which causes subsequent oxidative stress and energy metabolic failure in …

Barbigerone prevents scopolamine-induced memory impairment in rats by inhibiting oxidative stress and acetylcholinesterase levels

SA AlGhamdi, FA Al-Abbasi… - Royal Society …, 2023 - royalsocietypublishing.org
The current study was designed for the evaluation of barbigerone on memory loss. In this
experimental study, 24 Wistar rats (n= 6) were used. Control rats and scopolamine (SCOP) …

Boswellic acid attenuates scopolamine-induced neurotoxicity and dementia in rats: possible mechanism of action.

M Afzal, SI Alzarea, AM Quazi, I Kazmi, A Zafar, F Imam… - 2021 - cabidigitallibrary.org
Abstract Background and Objective: The oleo gum resin of plants belonging to the Boswellia
species contains pentacyclic triterpenic acids known as boswellic acid. This acid possesses …

Neuroprotective effects of betanin in mice with cerebral ischemia-reperfusion injury

W Thong-Asa, K Puenpha, T Lairaksa… - Experimental …, 2023 - jstage.jst.go.jp
Cerebral ischemia reperfusion (IR) injury as found in stroke is a complex and
heterogeneous disorder and closely related to disability and death. Today, nutraceuticals …

Verapamil attenuates scopolamine induced cognitive deficits by averting oxidative stress and mitochondrial injury–A potential therapeutic agent for Alzheimer's …

S Ponne, CR Kumar, R Boopathy - Metabolic Brain Disease, 2020 - Springer
Alzheimer's disease (AD) is a multifactorial disorder where amyloid beta (Aβ) plaques, Ca
2+ dysregulation, excessive oxidative stress, mitochondrial dysfunction and synaptic loss …

Friedelin attenuates neuronal dysfunction and memory impairment by inhibition of the activated JNK/NF-κB signalling pathway in scopolamine-induced mice model of …

M Sandhu, HM Irfan, SA Shah, M Ahmed, I Naz… - Molecules, 2022 - mdpi.com
Oxidative stress (OS) and c-Jun N-terminal kinase (JNK) are both key indicators implicated
in neuro-inflammatory signalling pathways and their respective neurodegenerative …

Neuropharmacological study on Capsaicin in Scopolamine-injected mice

S Tyagi, AK Thakur - Current Alzheimer Research, 2023 - ingentaconnect.com
Aim: To evaluate the potential beneficial role of Capsaicin in cognitive dysfunction,
mitochondrial impairment, and oxidative damage induced by scopolamine in mice …