Tuberculosis vaccine development: from classic to clinical candidates
J Li, A Zhao, J Tang, G Wang, Y Shi, L Zhan… - European Journal of …, 2020 - Springer
Abstract Bacillus Calmette-Guérin (BCG) has been in use for nearly 100 years and is the
only licensed TB vaccine. While BCG provides protection against disseminated TB in infants …
only licensed TB vaccine. While BCG provides protection against disseminated TB in infants …
An overview of the development of new vaccines for tuberculosis
E Whitlow, AS Mustafa, SNM Hanif - Vaccines, 2020 - mdpi.com
Currently, there is only one licensed vaccine against tuberculosis (TB), the Bacillus Calmette–
Guérin (BCG). Despite its protective efficacy against TB in children, BCG has failed to protect …
Guérin (BCG). Despite its protective efficacy against TB in children, BCG has failed to protect …
Tuberculosis vaccine: A journey from BCG to present
Tuberculosis (TB) is the leading cause of death worldwide due to an infectious disease,
causing around 1.6 million deaths each year. This situation has become more complicated …
causing around 1.6 million deaths each year. This situation has become more complicated …
Tuberculosis vaccine development: progress in clinical evaluation
Tuberculosis (TB) is the leading killer among all infectious diseases worldwide despite
extensive use of the Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccine. A safer …
extensive use of the Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccine. A safer …
Novel vaccination strategies against tuberculosis
P Andersen, SHE Kaufmann - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
The tuberculosis (TB) pandemic continues to rampage despite widespread use of the BCG
(Bacillus Calmette–Guérin) vaccine. Novel vaccination strategies are urgently needed to …
(Bacillus Calmette–Guérin) vaccine. Novel vaccination strategies are urgently needed to …
Development of tuberculosis vaccines in clinical trials: Current status
P Méndez‐Samperio - Scandinavian journal of immunology, 2018 - Wiley Online Library
Tuberculosis (TB) is an important infectious disease worldwide. Currently, Bacillus Calmette‐
Guérin (BCG) remains the only TB vaccine licensed for human use. This TB vaccine is …
Guérin (BCG) remains the only TB vaccine licensed for human use. This TB vaccine is …
Critical research concepts in tuberculosis vaccine development
G Delogu, R Manganelli… - Clinical Microbiology and …, 2014 - Wiley Online Library
A new and improved vaccine against tuberculosis (TB) would provide a powerful tool to
conquer one of the most insidious infectious diseases of mankind. Protection afforded by …
conquer one of the most insidious infectious diseases of mankind. Protection afforded by …
Tuberculosis vaccines in clinical trials
R Rowland, H McShane - Expert review of vaccines, 2011 - Taylor & Francis
Effective prophylactic and/or therapeutic vaccination is a key strategy for controlling the
global TB epidemic. The partial effectiveness of the existing TB vaccine, bacille Calmette …
global TB epidemic. The partial effectiveness of the existing TB vaccine, bacille Calmette …
The present and future of tuberculosis vaccinations
N Principi, S Esposito - Tuberculosis, 2015 - Elsevier
The clinical, social, and economic burden of tuberculosis (TB) remains high worldwide,
thereby highlighting the importance of TB prevention. The bacilli Calmette-Guérin (BCG) …
thereby highlighting the importance of TB prevention. The bacilli Calmette-Guérin (BCG) …
Vaccines against tuberculosis: where are we and where do we need to go?
THM Ottenhoff, SHE Kaufmann - PLoS pathogens, 2012 - journals.plos.org
In this review we discuss recent progress in the development, testing, and clinical evaluation
of new vaccines against tuberculosis (TB). Over the last 20 years, tremendous progress has …
of new vaccines against tuberculosis (TB). Over the last 20 years, tremendous progress has …