Activation of transient receptor potential vanilloid 4 is involved in neuronal injury in middle cerebral artery occlusion in mice
P Jie, Z Lu, Z Hong, L Li, L Zhou, Y Li, R Zhou… - Molecular …, 2016 - Springer
Transient receptor potential vanilloid 4 (TRPV4) is widely expressed in the central nervous
system and can be activated by multiple stimuli during cerebral ischemia. Recently, we …
system and can be activated by multiple stimuli during cerebral ischemia. Recently, we …
A pathophysiological role of TRPV1 in ischemic injury after transient focal cerebral ischemia in mice
J Miyanohara, H Shirakawa, K Sanpei… - Biochemical and …, 2015 - Elsevier
Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel with high
Ca 2+ permeability, which functions as a polymodal nociceptor activated by heat, protons …
Ca 2+ permeability, which functions as a polymodal nociceptor activated by heat, protons …
Inhibition of transient receptor potential vanilloid 1 attenuates blood–brain barrier disruption after traumatic brain injury in mice
D Yang, Y Jing, Y Liu, Z Xu, F Yuan, M Wang… - Journal of …, 2019 - liebertpub.com
Transient receptor potential vanilloid 1 (TRPV1) is expressed widely in the central nervous
system and is activated by various stimuli. Inhibiting TRPV1 has neuroprotective effects in …
system and is activated by various stimuli. Inhibiting TRPV1 has neuroprotective effects in …
Inhibition of transient receptor potential vanilloid‐1 confers neuroprotection, reduces tumor necrosis factor‐alpha, and increases IL‐10 in a rat stroke model
E Hakimizadeh, A Shamsizadeh… - Fundamental & …, 2017 - Wiley Online Library
Stroke is a major cause of mortality and long‐term disability in adults. Transient receptor
potential vanilloid‐1 (TRPV 1) plays a crucial role in neuroinflammation. In this study, the …
potential vanilloid‐1 (TRPV 1) plays a crucial role in neuroinflammation. In this study, the …
[HTML][HTML] Reduced Post-ischemic Brain Injury in Transient Receptor Potential Vanilloid 4 Knockout Mice
K Tanaka, S Matsumoto, T Yamada… - Frontiers in …, 2020 - frontiersin.org
Background and Purpose In the acute phase of ischemia-reperfusion, hypoperfusion
associated with ischemia and reperfusion in microvascular regions and disruption of the …
associated with ischemia and reperfusion in microvascular regions and disruption of the …
[HTML][HTML] Blockage of transient receptor potential vanilloid 4 inhibits brain edema in middle cerebral artery occlusion mice
Brain edema is an important pathological process during stroke. Activation of transient
receptor potential vanilloid 4 (TRPV4) causes an up-regulation of matrix metalloproteinases …
receptor potential vanilloid 4 (TRPV4) causes an up-regulation of matrix metalloproteinases …
[HTML][HTML] Activation of transient receptor potential vanilloid 4 increases NMDA-activated current in hippocampal pyramidal neurons
The glutamate excitotoxicity, mediated through N-methyl-d-aspartate receptors (NMDARs),
plays an important role in cerebral ischemia injury. Transient receptor potential vanilloid 4 …
plays an important role in cerebral ischemia injury. Transient receptor potential vanilloid 4 …
[HTML][HTML] Blockage of transient receptor potential vanilloid 4 alleviates myocardial ischemia/reperfusion injury in mice
Q Dong, J Li, Q Wu, N Zhao, C Qian, D Ding, B Wang… - Scientific Reports, 2017 - nature.com
Transient receptor potential vanilloid 4 (TRPV4) is a Ca2+-permeable nonselective cation
channel and can be activated during ischemia/reperfusion (I/R). This study tested whether …
channel and can be activated during ischemia/reperfusion (I/R). This study tested whether …
TRPV4 activation contributes functional recovery from ischemic stroke via angiogenesis and neurogenesis
CK Chen, PY Hsu, TM Wang, ZF Miao, RT Lin… - Molecular …, 2018 - Springer
The endothelial transient receptor potential cation channel subfamily V member 4 (TRPV4)
plays a crucial role in vascular remodeling; however, TRPV4-mediated angiogenesis after …
plays a crucial role in vascular remodeling; however, TRPV4-mediated angiogenesis after …
[HTML][HTML] Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK …
P Jie, Z Hong, Y Tian, Y Li, L Lin, L Zhou, Y Du… - Cell Death & …, 2015 - nature.com
Transient receptor potential vanilloid 4 (TRPV4) is a calcium-permeable cation channel that
is sensitive to cell swelling, arachidonic acid and its metabolites, epoxyeicosatrienoic acids …
is sensitive to cell swelling, arachidonic acid and its metabolites, epoxyeicosatrienoic acids …