Expanding opportunities to engineer mucosal vaccination with biomaterials

HF Haddad, EF Roe, JH Collier - Biomaterials Science, 2023 - pubs.rsc.org
Mucosal vaccines are receiving increasing interest both for protecting against infectious
diseases and for inducing therapeutic immune responses to treat non-infectious diseases …

The role of engineered materials in mucosal vaccination strategies

B Eshaghi, A Schudel, I Sadeghi, Z Chen… - Nature Reviews …, 2024 - nature.com
Mucosal pathogens, as exemplified by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), human immunodeficiency virus (HIV) and Mycobacterium tuberculosis, lead …

Immunology‐guided biomaterial design for mucosal cancer vaccines

S Ferber, RJ Gonzalez, AM Cryer… - Advanced …, 2020 - Wiley Online Library
Cancer of mucosal tissues is a major cause of worldwide mortality for which only palliative
treatments are available for patients with late‐stage disease. Engineered cancer vaccines …

Biomaterial approaches for understanding and overcoming immunological barriers to effective oral vaccinations

H Frizzell, KA Woodrow - Advanced Functional Materials, 2020 - Wiley Online Library
Oral vaccines have the potential to reduce cost, improve compliance, and induce immunity
at mucosal surfaces that are the first line of defense against infection. The gastrointestinal …

Current and new approaches for mucosal vaccine delivery

JH Rhee - Mucosal vaccines, 2020 - Elsevier
Mucosal surfaces are the interface between the host's internal milieu and the external
environment, and they have dual functions, serving as physical barriers to foreign antigens …

Mucosal vaccine design and delivery

KA Woodrow, KM Bennett, DD Lo - Annual review of biomedical …, 2012 - annualreviews.org
Mucosal surfaces are a major portal of entry for many human pathogens that are the cause
of infectious diseases worldwide. Vaccines capable of eliciting mucosal immune responses …

[HTML][HTML] Biomaterials for intranasal and inhaled vaccine delivery

D Cahn, M Amosu, K Maisel, GA Duncan - Nature reviews …, 2023 - nature.com
Delivery of vaccines by nasal sprays may enable more robust, protective mucosal immune
responses against infectious diseases, such as COVID-19, compared with intramuscular …

Integrating biomaterials and immunology to improve vaccines against infectious diseases

L Yenkoidiok-Douti, CM Jewell - ACS biomaterials science & …, 2020 - ACS Publications
Despite the success of vaccines in preventing many infectious diseases, effective vaccines
against pathogens with ongoing challenges—such as HIV, malaria, and tuberculosis …

Understanding Mucosal Physiology and Rationale of Formulation Design for Improved Mucosal Immunity

M Biswas, M Nurunnabi, Z Khatun - ACS Applied Bio Materials, 2024 - ACS Publications
The oral and nasal cavities serve as critical gateways for infectious pathogens, with
microorganisms primarily gaining entry through these routes. Our first line of defense against …

Recent advances on biodegradable polymeric carrier-based mucosal immunization: an overview

L Kaur, A Sharma, AK Yadav… - … Cells, Nanomedicine, and …, 2018 - Taylor & Francis
Mucosal administration of vaccine is most prevalent way to induce desired immunity against
various types of antigen and microbial in central and in addition, the peripheral blood in …